Skip to content

Advertisement

Articles

Page 1 of 4

  1. Content type: Research

    Diagnosing pancreatic ductal adenocarcinoma (PDAC) in the setting of metastasis with an unknown primary remains very challenging due to the lack of specific biomarkers. HNF-1B has been characterized as an impo...

    Authors: Michelle X. Yang, Ryan F. Coates, Abiy Ambaye, Juli-Anne Gardner, Richard Zubarick, Yuan Gao, Joan Skelly, James G. Liu and Mari Mino-Kenudson

    Citation: Biomarker Research 2018 6:25

    Published on:

  2. Content type: Letter to the Editor

    The prognosis of adult T-cell leukemia-lymphoma (ATL) remains very poor, and there is an urgent clinical need to investigate novel therapies for ATL. The expression of phosphatidylinositol 3-kinase-δ (PI3k-δ) ...

    Authors: Hiroo Katsuya, Lucy B. M. Cook, Aileen G. Rowan, Yorifumi Satou, Graham P. Taylor and Charles R. M. Bangham

    Citation: Biomarker Research 2018 6:24

    Published on:

  3. Content type: Research

    Carcinogenesis is a multistep process which involves interplay between the tumour cells and the matrix proteins. This occurs by adherence between the tumour cells and proteins in the extracellular matrix. VHL ...

    Authors: Sandeep Kondisetty, Krishnakumar N. Menon and Ginil Kumar Pooleri

    Citation: Biomarker Research 2018 6:23

    Published on:

  4. Content type: Short report

    Metronomic therapy has been gaining importance in the neoadjuvant setting of breast cancer treatment. Its clinical benefits may involve antiangiogenic machinery. Cancer cells induce angiogenesis to support tum...

    Authors: Roberto J. Arai, Vanessa Petry, Paulo M. Hoff and Max S. Mano

    Citation: Biomarker Research 2018 6:20

    Published on:

  5. Content type: Research

    For glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model phy...

    Authors: Kiera Walker, Nathaniel H. Boyd, Joshua C. Anderson, Christopher D. Willey and Anita B. Hjelmeland

    Citation: Biomarker Research 2018 6:22

    Published on:

  6. Content type: Letter to the Editor

    Chemerin is a recently discovered adipokine shown to be involved in both inflammatory and metabolic processes. Here, we demonstrate that chemerin serum levels are elevated in patients with multiple myeloma and...

    Authors: Marita Westhrin, Siv Helen Moen, Ida Bruun Kristensen, Glenn Buene, Anne Kærsgaard Mylin, Ingemar Turesson, Niels Abildgaard, Anders Waage and Therese Standal

    Citation: Biomarker Research 2018 6:21

    Published on:

  7. Content type: Research

    Colorectal cancer has significant impact on individuals and healthcare systems. Many genes have been identified to influence its pathogenesis. However, the genetic basis of mucinous tumor histology, an aggress...

    Authors: Michelle E. Penney, Patrick S. Parfrey, Sevtap Savas and Yildiz E. Yilmaz

    Citation: Biomarker Research 2018 6:17

    Published on:

  8. Content type: Short report

    Calretinin is the most widespread positive marker for the immunohistochemical identification of malignant mesothelioma (MM) and was proposed to serve as a blood-based biomarker. Functionally, evidence has accu...

    Authors: Walter Blum, Thomas Henzi, Hugues-Etienne Châtel-Soulet, Laszlo Pecze, Janine Wörthmüller Rodriguez, Bart Vrugt and Beat Schwaller

    Citation: Biomarker Research 2018 6:19

    Published on:

  9. Content type: Review

    Despite tremendous research efforts focused on diagnosis and treatment, pancreatic ductal adenocarcinoma remains the third leading cause of cancer-related death in the United States, with a 5-year overall surv...

    Authors: Shixiang Guo, Andrew Fesler, Huaizhi Wang and Jingfang Ju

    Citation: Biomarker Research 2018 6:18

    Published on:

  10. Content type: Case report

    Germline mutations in the RUNX1 transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet Disorders with predisposition to Acute Myeloid Leukaemi...

    Authors: Isaac KS Ng, Joanne Lee, Christopher Ng, Bustamin Kosmo, Lily Chiu, Elaine Seah, Michelle Meng Huang Mok, Karen Tan, Motomi Osato, Wee-Joo Chng, Benedict Yan and Lip Kun Tan

    Citation: Biomarker Research 2018 6:16

    Published on:

  11. Content type: Research

    Well-differentiated neuroendocrine tumors (NET) most frequently arise from the gastrointestinal tract (GI), pancreas, and lung. Patients often present as metastasis with an unknown primary, and the clinical ma...

    Authors: Michelle X. Yang, Ryan F. Coates, Abiy Ambaye, Valerie Cortright, Jeannette M. Mitchell, Alexa M. Buskey, Richard Zubarik, James G. Liu, Steven Ades and Maura M. Barry

    Citation: Biomarker Research 2018 6:15

    Published on:

  12. Content type: Research

    Inhaled allergen challenges are often used to evaluate novel asthma treatments in early phase clinical trials. Current novel therapeutic targets in asthma include phosphoinositide 3-kinases (PI3K) delta and ga...

    Authors: Thomas Southworth, Sarah Mason, Alan Bell, Isabel Ramis, Marta Calbet, Anna Domenech, Neus Prats, Montserrat Miralpeix and Dave Singh

    Citation: Biomarker Research 2018 6:14

    Published on:

  13. Content type: Case report

    GATA2 deficiency presents with a spectrum of phenotypes including increased susceptibility to viral and bacterial infections, multi-lineage cytopenias, aplastic anemia, leukemic transformation and lymphedema. ...

    Authors: Allen Sanyi, David L. Jaye, Cecilia B. Rosand, Amanda Box, Chandrakasan Shanmuganathan and Edmund K. Waller

    Citation: Biomarker Research 2018 6:13

    Published on:

  14. Content type: Short report

    Biomarkers promise biomolecular explanations as well as reliable diagnostics, stratification, and treatment strategies that have the potential to help mitigate the effects of disorders. While no reliable bioma...

    Authors: Daniel P. Howsmon, James B. Adams, Uwe Kruger, Elizabeth Geis, Eva Gehn and Juergen Hahn

    Citation: Biomarker Research 2018 6:12

    Published on:

  15. Content type: Research

    Yin Yang 1 (YY1) is a transcription factor that plays an important role during all stages of B cell differentiation. Several studies reported upregulation of YY1 in B cell derived lymphoma, indicating that it ...

    Authors: Jéssica Arribas Arranz, Dalia Nilufar Winter, Hans Günter Drexler and Sonja Eberth

    Citation: Biomarker Research 2018 6:11

    Published on:

  16. Content type: Review

    Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase and a catalytic component of PRC2, catalyzes tri-methylation of histone H3 at Lys 27 (H3K27me3) to regulate gene expression through epigenetic ma...

    Authors: Lu Gan, Yanan Yang, Qian Li, Yi Feng, Tianshu Liu and Weijian Guo

    Citation: Biomarker Research 2018 6:10

    Published on:

  17. Content type: Correction

    The original article [1] contains an error in Fig. 3 whereby the trend lines denoting Low & High E-cadherin were mistakenly labelled the opposite way around.

    Authors: W. Goto, S. Kashiwagi, Y. Asano, K. Takada, K. Takahashi, T. Hatano, T. Takashima, S. Tomita, H. Motomura, M. Ohsawa, K. Hirakawa and M. Ohira

    Citation: Biomarker Research 2018 6:9

    Published on:

    The original article was published in Biomarker Research 2017 5:19

  18. Content type: Research

    Sphingosine kinase (SphK) 2 has been implicated in the development of a range of cancers and inhibitors of this enzyme are currently in clinical trial. We have previously demonstrated a role for SphK2 in the d...

    Authors: Vicki Xie, Daochen Tong, Craig T. Wallington-Beddoe, Ken F. Bradstock and Linda J. Bendall

    Citation: Biomarker Research 2018 6:6

    Published on:

  19. Content type: Research

    Alzheimer’s disease (AD) is a most common dementia in elderly people. Since AD symptoms resemble those of other neurodegenerative diseases, including idiopathic normal pressure hydrocephalus (iNPH), it is diff...

    Authors: Yuki Nagata, Akiyoshi Hirayama, Satsuki Ikeda, Aoi Shirahata, Futaba Shoji, Midori Maruyama, Mitsunori Kayano, Masahiko Bundo, Kotaro Hattori, Sumiko Yoshida, Yu-ichi Goto, Katsuya Urakami, Tomoyoshi Soga, Kouichi Ozaki and Shumpei Niida

    Citation: Biomarker Research 2018 6:5

    Published on:

  20. Content type: Research

    Acute kidney injury (AKI) is a frequent complication of cardiac surgery. We sought prognostic combinations of postoperative biomarkers measured within 6 h of surgery, potentially in combination with cardiopulm...

    Authors: Allison Meisner, Kathleen F. Kerr, Heather Thiessen-Philbrook, Francis Perry Wilson, Amit X. Garg, Michael G. Shlipak, Peter Kavsak, Richard P. Whitlock, Steven G. Coca and Chirag R. Parikh

    Citation: Biomarker Research 2018 6:3

    Published on:

  21. Content type: Research

    Platelets support cancer growth and spread making platelet proteins candidates in the search for biomarkers.

    Authors: Marta Lomnytska, Rui Pinto, Susanne Becker, Ulla Engström, Sonja Gustafsson, Christina Björklund, Markus Templin, Jan Bergstrand, Lei Xu, Jerker Widengren, Elisabeth Epstein, Bo Franzén and Gert Auer

    Citation: Biomarker Research 2018 6:2

    Published on:

  22. Content type: Research

    Diagnosis of malaria in pregnancy is problematic due to the low sensitivity of conventional diagnostic tests (rapid diagnostic test and microscopy), which is exacerbated due to low peripheral parasite densitie...

    Authors: E. Ruizendaal, H. D. F. H. Schallig, J. Bradley, M. Traore-Coulibaly, P. Lompo, U. d’Alessandro, S. Scott, F. Njie, S. H. Zango, O. Sawadogo, M. D. de Jong, H. Tinto and P. F. Mens

    Citation: Biomarker Research 2017 5:34

    Published on:

  23. Content type: Research

    Selective kinase and immune checkpoint inhibitors, and their combinations, have significantly improved the survival of patients with advanced metastatic melanoma. Not all patients will respond to treatment how...

    Authors: Su Yin Lim, Jenny H. Lee, Sarah J. Welsh, Seong Beom Ahn, Edmond Breen, Alamgir Khan, Matteo S. Carlino, Alexander M. Menzies, Richard F. Kefford, Richard A. Scolyer, Georgina V. Long and Helen Rizos

    Citation: Biomarker Research 2017 5:32

    Published on:

  24. Content type: Research

    Quantitative proteomics allows for the discovery and functional investigation of blood-based pre-diagnostic biomarkers for early cancer detection. However, a major limitation of proteomic investigations in bio...

    Authors: Christine Y. Yeh, Ravali Adusumilli, Majlinda Kullolli, Parag Mallick, Esther M. John and Sharon J. Pitteri

    Citation: Biomarker Research 2017 5:30

    Published on:

  25. Content type: Research

    Monomeric laminin-γ2 in urine is a potential biomarker for bladder cancer. However, the current detection system uses an antibody that cannot discriminate between monomeric laminin-γ2 and the heterotrimeric γ2...

    Authors: Masatoshi Nakagawa, Takashi Karashima, Masayuki Kamada, Eisaku Yoshida, Toru Yoshimura, Masanori Nojima, Keiji Inoue, Taro Shuin, Motoharu Seiki and Naohiko Koshikawa

    Citation: Biomarker Research 2017 5:29

    Published on:

  26. Content type: Methodology

    The pattern of serotonin transporter clustering on the plasma membrane of lymphocytes extracted from human whole blood samples has been identified as a putative biomarker of therapeutic efficacy in major depre...

    Authors: Raquel Romay-Tallon, Tania Rivera-Baltanas, Josh Allen, Jose M. Olivares, Lisa E. Kalynchuk and Hector J. Caruncho

    Citation: Biomarker Research 2017 5:27

    Published on:

  27. Content type: Research

    Because soluble (or secreted) amyloid precursor protein-β (sAPPβ) and -α (sAPPα) possibly reflect pathological features of Alzheimer’s disease (AD), they are potential biomarker candidates for dementia disorde...

    Authors: Wataru Araki, Kotaro Hattori, Kazutomi Kanemaru, Yuma Yokoi, Yoshie Omachi, Harumasa Takano, Masuhiro Sakata, Sumiko Yoshida, Tadashi Tsukamoto, Miho Murata, Yuko Saito, Hiroshi Kunugi, Yu-ichi Goto, Utako Nagaoka, Masahiro Nagao, Takashi Komori…

    Citation: Biomarker Research 2017 5:28

    Published on:

  28. Content type: Research

    The purpose of this study was to investigate the potential of cerebrospinal fluid miRNAs as diagnostic biomarkers of acute ischemic stroke using three different profiling techniques in order to identify and by...

    Authors: Sofie Sølvsten Sørensen, Ann-Britt Nygaard, Anting Liu Carlsen, Niels H. H. Heegaard, Mads Bak and Thomas Christensen

    Citation: Biomarker Research 2017 5:24

    Published on:

  29. Content type: Review

    Because the prevalence of antibiotic resistance markedly increases with time worldwide, anti-H. pylori treatment is continuing to be a great challenge forsphysicians in clinical practice. The Real-world Practice ...

    Authors: Chih-Chieh Huang, Kuo-Wang Tsai, Tzung-Jiun Tsai and Ping-I Hsu

    Citation: Biomarker Research 2017 5:23

    Published on:

  30. Content type: Review

    Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumo...

    Authors: Cheng Zhang, Jun Liu, Jiang F. Zhong and Xi Zhang

    Citation: Biomarker Research 2017 5:22

    Published on:

  31. Content type: Research

    Breast cancer, the most commonly diagnosed cancer among women and leading cause of cancer-related deaths worldwide, exhibits aggressive behavior in indigenous African women evidenced by high histologic grade t...

    Authors: Benjamin Arko-Boham, Justice Tanihu Lomotey, Emmanuel Nomo Tetteh, Emmanuel Ayitey Tagoe, Nii Ayite Aryee, Ewurama Ampadu Owusu, Isaac Okai, Richard Michael Blay and Joe-Nat Clegg-Lamptey

    Citation: Biomarker Research 2017 5:21

    Published on:

  32. Content type: Letter to the Editor

    Analysis of databases from the human genome project (HGP), the 1000 Genomes Project (1KGP), and The Cancer Genome Atlas (TCGA) revealed bacterial DNA integration into the human somatic genome, particularly in ...

    Authors: Saveen Sidhoo, Jesusa L. Rosales and Ki-Young Lee

    Citation: Biomarker Research 2017 5:20

    Published on:

  33. Content type: Research

    Circulating tumor cells (CTCs) are linked to metastatic relapse and are regarded as a prognostic marker for human cancer. High expression of plakoglobin, a cell adhesion protein, within the primary tumor is po...

    Authors: Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Masahiko Ohsawa, Kosei Hirakawa and Masaichi Ohira

    Citation: Biomarker Research 2017 5:19

    Published on:

    The Correction to this article has been published in Biomarker Research 2018 6:9

  34. Content type: Short report

    Alternate BRAF splicing is the most common mechanism of acquired resistance to BRAF inhibitor treatment in melanoma. Recently, alternate BRAF exon 4–8 splicing was shown to involve an intronic mutation, locate...

    Authors: Gulietta M. Pupo, Suzanah C. Boyd, Carina Fung, Matteo S. Carlino, Alexander M. Menzies, Bernadette Pedersen, Peter Johansson, Nicholas K. Hayward, Richard F. Kefford, Richard A. Scolyer, Georgina V. Long and Helen Rizos

    Citation: Biomarker Research 2017 5:17

    Published on:

  35. Content type: Case report

    Babesiosis is endemic in selected areas in North America. Babesia infection is commonly associated with anemia, thrombocytopenia, hyponatremia and elevated liver enzymes. Autoimmune hemolytic anemia (AIHA) is ...

    Authors: Roshni Narurkar, Aleksandra Mamorska-Dyga, John C. Nelson and Delong Liu

    Citation: Biomarker Research 2017 5:14

    Published on:

  36. Content type: Case series

    Low albumin levels and low lymphocyte counts are intra hospital conditions that exert a negative influence on prognosis, healing and length of hospitalization. The study aimed to analyze the correlation betwee...

    Authors: Antonio E. Pontiroli, Lara Loreggian, Marco P. L. Rovati, Elena De Patto, Laura Folini, Federico Raveglia, Matilde De Simone, Alessandro Baisi and Ugo Cioffi

    Citation: Biomarker Research 2017 5:13

    Published on:

  37. Content type: Research

    Urothelial bladder cancer (UBC) is a disease that often is discovered when the tumour is non-muscle invasive, i.e. in Ta or T1 stage. Some patients will progress into muscle-invasive disease, a potentially dea...

    Authors: Karolina Boman, Gustav Andersson, Christoffer Wennersten, Björn Nodin, Göran Ahlgren and Karin Jirström

    Citation: Biomarker Research 2017 5:10

    Published on:

2017 Journal Metrics

  • Speed
    33 days from submission to first decision
    76 days from submission to acceptance
    12 days from acceptance to publication

    Usage 
    151,816 Downloads
    74 Altmetric mentions

Advertisement