Biomarker Research

Featured review: EZH2 as a therapeutic target for multiple myeloma

This article by Dr. Tremblay-LeMay et al. reviews the evidence supporting the role of EZH2 in MM pathophysiology and drug resistance, with an emphasis on interactions between EZH2 and microRNAs, as well as the prognostic significance of EZH2 expression in MM. Furthermore, results from the pre-clinical studies of EZH2 inhibition in MM and currently available interim results from clinical trials of EZH2 inhibitors in haematological malignancies are presented.

Content type: Review
| 12 February 2019

Measuring disease activity and predicting response to intravenous immunoglobulin in chronic inflammatory demyelinating polyneuropathy

Authors: Anthony Khoo, Joseph Frasca and David Schultz
Content type: Letter to the Editor
| 14 January 2019

Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma

Authors: Sebastian Lundgren, Helena Fagerström-Vahman, Cheng Zhang, Liv Ben-Dror, Adil Mardinoglu, Mathias Uhlen, Björn Nodin and Karin Jirström
Content type: Letter to the Editor
| 14 January 2019

Pluripotency markers are differentially induced by IGF1 and bFGF in cells from patients’ lesions of large/giant congenital melanocytic nevi

Authors: Dipanjan Basu, Cláudia M. Salgado, Janki R. Patel, Joie Zabec, Ryan M. Hoehl, Bruce Bauer and Miguel Reyes-Múgica
Content type: Research
| 29 December 2018

Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

Authors: M. J. Morris, L. B. Hesson, R. C. Poulos, R. L. Ward, J. W. H. Wong and N. A. Youngson
Content type: Short report
| 7 December 2018

OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus

Authors: Natalia Castaño-Rodríguez, Georgia L. Popple, Gloria Liliana Porras-Hurtado, José Luis Cardona-Deazza, Juan José Montoya-Martinez, Antonio Javier Cadavid-Velez, Héctor William Toro-Hidalgo, Alba Ruth Cobo-Alvarado, Ofelia del Socorro Hincapié-Rincón, Stephen M. Riordan and Nadeem O. Kaakoush

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Content type: Research
| 7 April 2016

The combinatorial approach of laser-captured microdissection and reverse transcription quantitative polymerase chain reaction accurately determines HER2 status in breast cancer

Authors: Elisabeth Hofmann, Rita Seeboeck, Nico Jacobi, Peter Obrist, Samuel Huter, Christian Klein, Kamil Oender, Christoph Wiesner, Harald Hundsberger and Andreas Eger
Content type: Review
| 1 April 2013

Metabolomic analyses for atherosclerosis, diabetes, and obesity

Authors: Fuyong Du, Anthony Virtue, Hong Wang and Xiao-Feng Yang
Content type: Review
| 7 January 2014

Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases

Authors: Jiyeon Yang, Lixiao Zhang, Caijia Yu, Xiao-Feng Yang and Hong Wang
Content type: Review
| 10 February 2014

CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies

Authors: Ugo Testa, Elvira Pelosi and Arthur Frankel
Content type: Review
| 5 February 2013

Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy

Authors: Kai Zhu, Zhi Dai and Jian Zhou

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Editors-in-Chief

Chung-Tsen Hsueh, Loma Linda University

Delong Liu, New York Medical College

Aims and scope

Biomarker Research is an open access, peer-reviewed journal that encompasses all aspects of biomarker investigation. Biomarker Research aims to publish original discoveries, novel concepts, commentaries and reviews related to biomarker investigation from all biomedical disciplines.

The study of biomarkers has evolved rapidly in the advance of personalized medicine and individual health. The identification and validation of biomarkers in drug discovery/development and in disease diagnosis, treatment, prognosis, and prevention play an essential role in the genome era. With a quick turnaround time from submission to publication and online feedback from readers, Biomarker Research strives to provide fast dissemination of novel findings and new knowledge.

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Featured review: EZH2 as a therapeutic target for multiple myeloma

Articles

Measuring disease activity and predicting response to intravenous immunoglobulin in chronic inflammatory demyelinating polyneuropathy

Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma

Pluripotency markers are differentially induced by IGF1 and bFGF in cells from patients’ lesions of large/giant congenital melanocytic nevi

Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus

The combinatorial approach of laser-captured microdissection and reverse transcription quantitative polymerase chain reaction accurately determines HER2 status in breast cancer

Metabolomic analyses for atherosclerosis, diabetes, and obesity

Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases

CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies

Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy

Editors-in-Chief

Aims and scope

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