Skip to main content

Advertisement

Articles

Page 3 of 5

  1. Glucocorticoids (GCs) remain the first line treatment for almost all non-infectious inflammatory diseases, ranging from acute asthma to rheumatoid arthritis. However, across all conditions, patients have a var...

    Authors: Emily L. Williams, Madeleine L. Stimpson, Peter L. Collins, Doyo G. Enki, Ashish Sinha, Richard W. Lee and Ashwin D. Dhanda

    Citation: Biomarker Research 2016 4:26

    Content type: Methodology

    Published on:

  2. There is an urgent need for new anti-malaria drugs with broad therapeutic potential and novel mode of action, for effective treatment and to overcome emerging drug resistance. Plant-derived anti-malarials rema...

    Authors: Protus Arrey Tarkang, Regina Appiah-Opong, Michael F. Ofori, Lawrence S. Ayong and Alexander K. Nyarko

    Citation: Biomarker Research 2016 4:25

    Content type: Review

    Published on:

  3. Mild cognitive impairment (MCI) is an intermediate state between normal aging and dementia including Alzheimer’s disease. Early detection of dementia, and MCI, is a crucial issue in terms of secondary preventi...

    Authors: Mitsunori Kayano, Sayuri Higaki, Jun-ichi Satoh, Kenji Matsumoto, Etsuro Matsubara, Osamu Takikawa and Shumpei Niida

    Citation: Biomarker Research 2016 4:22

    Content type: Methodology

    Published on:

  4. It is crucial to develop new antischistosomal drugs since there is no vaccine and the whole world is relying on only a single drug for the treatment of schistosomiasis. One of the obstacles to the development ...

    Authors: Emmanuel Mouafo Tekwu, William Kofi Anyan, Daniel Boamah, Kofi Owusu Baffour-Awuah, Stephanie Keyetat Tekwu, Veronique Penlap Beng, Alexander Kwadwo Nyarko and Kwabena Mante Bosompem

    Citation: Biomarker Research 2016 4:21

    Content type: Review

    Published on:

  5. Pancreatic cancer is characterized as a disease with low survival and high mortality because of no effective diagnostic and therapeutic strategies available in clinic. Conventional clinical diagnostic methods ...

    Authors: Jing Huang, Jianzhou Liu, Kevin Chen-Xiao, Xuemei Zhang, W. N. Paul Lee, Vay Liang W. Go and Gary Guishan Xiao

    Citation: Biomarker Research 2016 4:20

    Content type: Review

    Published on:

  6. Population studies showed that patients with JAK2 V617F mutation had increased mortality, and increased risk of any cancer, hematologic cancer, and myeloproliferative disease.

    Authors: Kenneth G. Liu, Amit Verma, Olga Derman, Noah Kornblum, Murali Janakiram, Ira Braunschweig and Ramakrishna Battini

    Citation: Biomarker Research 2016 4:19

    Content type: Case report

    Published on:

  7. Bone marrow sarcoidosis is extremely rare. The association between sarcoidosis and lymphoproliferative disorders has been previously speculated, although the diagnosis of sarcoidosis often precedes any hematol...

    Authors: John Gubatan, Xiaohui Wang, Abner Louissaint, Anuj Mahindra and John Vanderpool

    Citation: Biomarker Research 2016 4:18

    Content type: Case report

    Published on:

  8. Extramedullary hematopoeisis (EMH) can occur in various physiological and pathologic states. The spleen is the most common site of EMH.

    Authors: Tasleem Katchi, Krishna Kolandaivel, Pallavi Khattar, Taliya Farooq, Humayun Islam and Delong Liu

    Citation: Biomarker Research 2016 4:17

    Content type: Case report

    Published on:

  9. Acute myeloid leukemia (AML) is commonly characterized by several chromosomal abnormalities resulting in the formation of chimeric genes that play various roles in leukemogenesis. Translocations resulting in the

    Authors: Carlos A. Tirado, Ken Siangchin, David S. Shabsovich, Maryam Sharifian and Gary Schiller

    Citation: Biomarker Research 2016 4:16

    Content type: Short report

    Published on:

  10. Chronic myeloid leukemia (CML) comprises ~3 % of pediatric leukemia. Although therapy with tyrosine kinase inhibitors (TKIs) is highly effective for CML, multiple factors have been identified as predictive of ...

    Authors: Margaret Lewen, Renee Gresh, Maria Queenan, Michele Paessler, Vinodh Pillai, Elizabeth Hexner, Dale Frank, Adam Bagg, Richard Aplenc, Emi Caywood and Gerald Wertheim

    Citation: Biomarker Research 2016 4:14

    Content type: Case report

    Published on:

  11. Oxaliplatin induced peripheral neurotoxicity (OXIPN) is the major dose-limiting and long-lasting side effect of oxaliplatin. N-3 PUFAs have neuroprotective property via their effects on voltage-gated ion chann...

    Authors: Ali Esfahani, Mohammad hossein Somi, Hormoz Ayromlou, Alireza Nikanfar, Mohammad Asghari Jafarabadi, Bina Eftekhar Sadat and Zohreh Ghoreishi

    Citation: Biomarker Research 2016 4:13

    Content type: Research

    Published on:

  12. Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease with variable clinical outcome, accounting for at least 25-30 % of adult non-Hodgkin lymphomas. Approximately one third of DLBCL patients are not ...

    Authors: Linn Reinholdt, Maria Bach Laursen, Alexander Schmitz, Julie Støve Bødker, Lasse Hjort Jakobsen, Martin Bøgsted, Hans Erik Johnsen and Karen Dybkær

    Citation: Biomarker Research 2016 4:12

    Content type: Research

    Published on:

  13. Reprogrammed metabolism is a new hallmark of cancer. In many types of cancer, most of the genes in the glycolytic pathway are overexpressed, reflecting an essential shift of metabolism during cancer developmen...

    Authors: Zhenyu Sun, Xiaofeng Chen, Gan. Wang, Liang Li, Guofeng Fu, Matthew Kuruc and Xing Wang

    Citation: Biomarker Research 2016 4:11

    Content type: Research

    Published on:

  14. There is an increasing amount of reports on IFITM1 (interferon-inducible transmembrane protein 1) in various malignancies. The aim of this study was to examine the expression of IFITM1 and its prognostic signi...

    Authors: David Borg, Charlotta Hedner, Alexander Gaber, Björn Nodin, Richard Fristedt, Karin Jirström, Jakob Eberhard and Anders Johnsson

    Citation: Biomarker Research 2016 4:10

    Content type: Research

    Published on:

  15. Disruption of alternative splicing in apoptotic factors has been associated to chronic lymphocytic leukemia among other cancers and hematological malignancies. The proapoptotic proteins Caspase-9 and PP2Acα ar...

    Authors: Leticia Domínguez-Berrocal, Xiguang Zhang, Jean Marc Zini, Jesús Fominaya, Angelita Rebollo and Jerónimo Bravo

    Citation: Biomarker Research 2016 4:9

    Content type: Short report

    Published on:

  16. HER2 expression in breast cancer correlates with increased metastatic potential, higher tumor recurrence rates and improved response to targeted therapies. Fluorescence in situ hybridization (FISH) and immunohist...

    Authors: Elisabeth Hofmann, Rita Seeboeck, Nico Jacobi, Peter Obrist, Samuel Huter, Christian Klein, Kamil Oender, Christoph Wiesner, Harald Hundsberger and Andreas Eger

    Citation: Biomarker Research 2016 4:8

    Content type: Research

    Published on:

  17. Patients with common variable immunodeficiency (CVID) have an increased risk of developing lymphoproliferative diseases, including non-Hodgkins lymphoma (Blood 116:1228–1234, 2010; Blood 119:1650–7, 2012). The...

    Authors: Efren Rael, Kevin Rakszawski, Kristian Koller, Michael Bayerl, Manish Butte and Hong Zheng

    Citation: Biomarker Research 2016 4:7

    Content type: Case report

    Published on:

  18. Genomic instability and clonal evolution are hallmarks of progressing chronic myeloid leukemia (CML). Recently, we have shown that clonal evolution and blast crisis correlate with altered expression and activi...

    Authors: Wiltrud Prinzhorn, Michael Stehle, Helga Kleiner, Sabrina Ruppenthal, Martin C. Müller, Wolf-Karsten Hofmann, Alice Fabarius and Wolfgang Seifarth

    Citation: Biomarker Research 2016 4:5

    Content type: Research

    Published on:

  19. Stage I lung adenocarcinoma is usually not treated with adjuvant chemotherapy; however, around half of these patients do not survive 5 years. Therefore, a reliable prognostic biomarker for early stage patients...

    Authors: Marcin Krzystanek, Judit Moldvay, David Szüts, Zoltan Szallasi and Aron Charles Eklund

    Citation: Biomarker Research 2016 4:4

    Content type: Research

    Published on:

  20. RECQ helicase family members act as guardians of the genome to assure proper DNA metabolism in response to genotoxic stress. Hematological malignancies are characterized by genomic instability that is possibly...

    Authors: Elena Viziteu, Alboukadel Kassambara, Philippe Pasero, Bernard Klein and Jerome Moreaux

    Citation: Biomarker Research 2016 4:3

    Content type: Research

    Published on:

  21. Acute lymphoblastic leukemia is the most common malignant cancer in childhood. The signs and symptoms of childhood cancer are difficult to recognize, as it is not the first diagnosis to be considered for nonsp...

    Authors: Marcio de Souza Cavalcante, José Camilo Torres-Romero, Marina Duarte Pinto Lobo, Frederico Bruno Mendes Batista Moreno, Leonardo Primo Bezerra, Diego Silva Lima, Jesamar Correia Matos, Renato de Azevedo Moreira and Ana Cristina de Oliveira Monteiro-Moreira

    Citation: Biomarker Research 2016 4:1

    Content type: Research

    Published on:

  22. Plasmablastic lymphoma (PBL) is a rare and aggressive subtype of non-Hodgkin diffuse large B-cell lymphoma originally with a predilection to the oral cavity of patients infected with HIV. However, PBL of extra...

    Authors: Makoto Hirosawa, Hiroaki Morimoto, Ryo Shibuya, Shohei Shimajiri and Junichi Tsukada

    Citation: Biomarker Research 2015 3:28

    Content type: Case report

    Published on:

  23. Blood transfusion is central in the prevention and treatment of certain chronic complications of sickle cell disease. It is indispensible in correcting anaemias as well as in the practice of exchange blood tra...

    Authors: Umar Kangiwa, Obike Ibegbulam, Sunday Ocheni, Anazoeze Madu and Ndakosu Mohammed

    Citation: Biomarker Research 2015 3:26

    Content type: Research

    Published on:

  24. Asian Indians have a high incidence of type 2 diabetes, but factors associated with glycemic progression in this population are not understood. MicroRNAs are emerging as important mediators of glucose homeosta...

    Authors: Elena Flowers, Meghana Gadgil, Bradley E. Aouizerat and Alka M. Kanaya

    Citation: Biomarker Research 2015 3:22

    Content type: Research

    Published on:

  25. The paper by Rachidi et al. suggests that antiplatelet drugs may play a role in ameliorating the clinical outcome in a large series of patients with head and neck cancer managed with either surgery or radiation. ...

    Authors: Carlo Furlan, Agostino Steffan, Jerry Polesel, Marco Trovo, Carlo Gobitti, Emanuela Vaccher, Diego Serraino, Luigi Barzan and Giovanni Franchin

    Citation: Biomarker Research 2015 3:25

    Content type: Letter to the Editor

    Published on:

  26. The presence of chromosomal abnormalities is one of the most important criteria for leukaemia diagnosis and management. Infant leukaemia is a rare disease that affects children in their first year of life. It ...

    Authors: Sabrina Tosi, Yasser Mostafa Kamel, Temitayo Owoka, Concetta Federico, Tony H. Truong and Salvatore Saccone

    Citation: Biomarker Research 2015 3:21

    Content type: Review

    Published on:

  27. Rheumatoid arthritis (RA) is a chronic inflammatory disease that preferentially affects joints, and characterized by an approximately two-fold increased risk of cardiovascular diseases compared with the genera...

    Authors: Mickael Essouma and Jean Jacques N. Noubiap

    Citation: Biomarker Research 2015 3:24

    Content type: Review

    Published on:

  28. Alcoholic hepatitis (AH) is caused by acute inflammation of the liver in patients that consume excessive amounts of alcohol, usually in a background of cirrhosis. AH can range from mild to severe, life threate...

    Authors: Erik Rahimi and Jen-Jung Pan

    Citation: Biomarker Research 2015 3:20

    Content type: Review

    Published on:

  29. Immune thrombocytopenia is an autoimmune disease with abnormal biomarkers. Immune thrombocytopenia pathogenesis is a complicated process in which the patient’s immune system is activated by platelet autoantige...

    Authors: Lingjia Yu, Chunmei Zhang, Liping Zhang, Yongyu Shi and Xuebin Ji

    Citation: Biomarker Research 2015 3:19

    Content type: Review

    Published on:

  30. Prorenin and renin are both involved in atherosclerosis. However, the role of plasma prorenin and renin in the development and progression of coronary artery disease (CAD) is still not clear. Thus, we aimed to...

    Authors: Gakuro Yoshida, Masanori Kawasaki, Ichijiro Murata, Yuka Hayakawa, Takuma Aoyama, Nagisa Miyazaki, Yoshihisa Yamada, Kazuhiko Nishigaki, Yoshie Arai, Fumiaki Suzuki and Shinya Minatoguchi

    Citation: Biomarker Research 2015 3:18

    Content type: Research

    Published on:

  31. Mutations of the BCR-ABL1 fusion gene represent a well established cause of resistance to tyrosine kinase inhibitors. Among the different mutations identified T315I is of particular concern since it is not effect...

    Authors: Valentina Rosso, Enrico Bracco, Roberto Pedrola, Sonia Carturan, Elisabetta Signorino, Jessica Petiti, Chiara Calabrese, Paolo Nicoli, Marco De Gobbi, Valentina Gaidano, Daniela Gallo, Stefano Ulisciani, Carmen Fava, Giovanna Rege-Cambrin, Francesco Frassoni, Giuseppe Saglio…

    Citation: Biomarker Research 2015 3:15

    Content type: Methodology

    Published on:

  32. A 72-year-old woman was diagnosed with uveal melanoma, peritoneal mesothelioma and a primary biliary tract adenocarcinoma. She had a strong family history of mesothelioma as well as other malignancies includin...

    Authors: Sonja Klebe, Jack Driml, Masaki Nasu, Sandra Pastorino, Amirmasoud Zangiabadi, Douglas Henderson and Michele Carbone

    Citation: Biomarker Research 2015 3:14

    Content type: Case report

    Published on:

  33. Fanconi Anemia (FA) is an inherited disorder characterized by the variable presence of multiple congenital somatic abnormalities, bone marrow failure and cancer susceptibility. Medulloblastoma (MB) has been de...

    Authors: Evelina Miele, Angela Mastronuzzi, Agnese Po, Andrea Carai, Vincenzo Alfano, Annalisa Serra, Giovanna Stefania Colafati, Luisa Strocchio, Manila Antonelli, Francesca Romana Buttarelli, Massimo Zani, Sergio Ferraro, Amelia Buffone, Alessandra Vacca, Isabella Screpanti, Felice Giangaspero…

    Citation: Biomarker Research 2015 3:13

    Content type: Case report

    Published on:

  34. Breast cancer circulating biomarkers include carcinoembryonic antigen and carbohydrate antigen 15–3, which are used for patient follow-up. Since sensitivity and specificity are low, novel and more useful bioma...

    Authors: Alessandra Mangolini, Manuela Ferracin, Maria Vittoria Zanzi, Elena Saccenti, Sayda Omer Ebnaof, Valentina Vultaggio Poma, Juana M. Sanz, Angela Passaro, Massimo Pedriali, Antonio Frassoldati, Patrizia Querzoli, Silvia Sabbioni, Paolo Carcoforo, Alan Hollingsworth and Massimo Negrini

    Citation: Biomarker Research 2015 3:12

    Content type: Research

    Published on:

  35. Rearrangements involving ETV6 (12p13) are among the most common structural abnormalities in pediatric B-cell acute lymphoblastic leukemia (B-ALL) and involve numerous partner genes. Additionally, the t(8;14)(q11....

    Authors: Carlos A. Tirado, David Shabsovich, Yeun Kim, Peter Traum, Sheeja Pullarkat, Michael Kallen and Nagesh Rao

    Citation: Biomarker Research 2015 3:11

    Content type: Case report

    Published on:

    The Erratum to this article has been published in Biomarker Research 2015 3:27

  36. Primary hepatic lymphoma (PHL) is an extremely rare disease, frequently associated with viruses such as hepatitis B virus (HBV), hepatitis C virus (HCV), and human immune deficiency virus (HIV). On the other h...

    Authors: Ai Kawahara, Junichi Tsukada, Takahiro Yamaguchi, Takefumi Katsuragi and Takehiro Higashi

    Citation: Biomarker Research 2015 3:10

    Content type: Case report

    Published on:

  37. Ovarian and triple-negative breast cancers with BRCA1 or BRCA2 loss are highly sensitive to treatment with PARP inhibitors and platinum-based cytotoxic agents and show an accumulation of genomic scars in the f...

    Authors: Andrea M Marquard, Aron C Eklund, Tejal Joshi, Marcin Krzystanek, Francesco Favero, Zhigang C Wang, Andrea L Richardson, Daniel P Silver, Zoltan Szallasi and Nicolai J Birkbak

    Citation: Biomarker Research 2015 3:9

    Content type: Research

    Published on:

  38. Glioblastoma (GBM) is a highly angiogenic malignancy that is resistant to standard therapy; neo-formed vessels of this aggressive malignancy are thought to arise by sprouting of pre-existing brain capillaries....

    Authors: Jin-ming Mao, Jing Liu, Geng Guo, Xing-gang Mao and Chang-xin Li

    Citation: Biomarker Research 2015 3:8

    Content type: Review

    Published on:

  39. Adiponectin has been recognized as a potent regulator of metabolism possessing anti-inflammatory and anti-atherogenic functions and inversely associated with increasing incidents of type 2 diabetes and obesity...

    Authors: Mohamed Abu-Farha, Kazem Behbehani and Naser Elkum

    Citation: Biomarker Research 2015 3:7

    Content type: Letter to the Editor

    Published on:

Annual Journal Metrics

On the blog

Advertisement