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  1. Content type: Research

    Natural killer cells comprise the body’s first line of defense against virus-infected cells. As is true of all lymphocytes, natural killer cell malignancies can develop, however natural killer cell leukemias c...

    Authors: Jon Crosbie, Marc Magnussen, Ryan Dornbier, Alexandra Iannone and Timothy A Steele

    Citation: Biomarker Research 2013 1:33

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  2. Content type: Review

    Although palliative chemotherapy has been shown to prolong survival and improve quality of life, the survival of advanced gastric cancer (AGC) patients remains poor. With the advent of targeted therapy, many m...

    Authors: Miao-zhen Qiu and Rui-hua Xu

    Citation: Biomarker Research 2013 1:32

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  3. Content type: Short report

    B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy in pediatric patients and the leading cause of cancer-related death in children and young adults. Translocations of 9p24 involving JAK2 (9...

    Authors: Carlos A Tirado, David Shabsovich, Matthew DeNicola, Dinesh Rao, Lynn Yang, Rolando Garcia and Nagesh Rao

    Citation: Biomarker Research 2013 1:31

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  4. Content type: Research

    Glioblastoma Multiforme (GBM) is the most common primary malignant tumor of the central nervous system. Standard of care includes maximal resection followed by chemoradiotherapy. Tumors need adequate perfusion...

    Authors: Andra V Krauze, Minhee Won, Christian Graves, Ben W Corn, Thierry M Muanza, Steven P Howard, Arul Mahadevan, Christopher J Schultz, Michael L Haas, Minesh P Mehta and Kevin A Camphausen

    Citation: Biomarker Research 2013 1:29

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  5. Content type: Short report

    Huntington Disease (HD) is a progressive neurological disorder, with pathological manifestations in brain areas and in periphery caused by the ubiquitous expression of mutant Huntingtin protein. Transcriptiona...

    Authors: Daniela Diamanti, Elisa Mori, Danny Incarnato, Federico Malusa, Costanza Fondelli, Letizia Magnoni and Giuseppe Pollio

    Citation: Biomarker Research 2013 1:28

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  6. Content type: Review

    A higher concentration of high density lipoprotein cholesterol (HDL-C) in ex-smokers than smokers has consistently been observed. Better evidence of quitting effects comes from within-subject changes. We exten...

    Authors: Barbara A Forey, John S Fry, Peter N Lee, Alison J Thornton and Katharine J Coombs

    Citation: Biomarker Research 2013 1:26

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  7. Content type: Review

    Carbohydrate antigen 125 (CA-125), traditionally a tumor marker for screening, diagnosis, and monitoring in ovarian malignancy, had recently been shown increasing evidence and more extensively recognized/explo...

    Authors: Chung-Lieh Hung, Ta-Chuan Hung, Yau-Hui Lai, Chi-Sheng Lu, Yih-Jer Wu and Hung-I Yeh

    Citation: Biomarker Research 2013 1:25

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  8. Content type: Research

    The Cancer Testis Antigens (CTAs) are a group of genes that are highly expressed in the normal testis and several types of cancer. Due to their restricted expression in normal adult tissues, CTAs have been att...

    Authors: John J Kim, Krithika Rajagopalan, Basil Hussain, Brenten H Williams, Prakash Kulkarni and Steven M Mooney

    Citation: Biomarker Research 2013 1:22

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  9. Content type: Research

    Toll-like receptor 4 (TLR4) and its co-receptor CD14 play a major role in innate immunity by recognizing PAMPs and signal the activation of adaptive responses. These receptors can recognize endogenous ligands ...

    Authors: Tarak Dhaouadi, Imen Sfar, Youssra Haouami, Leila Abdelmoula, Sami Turki, Lamia Ben Hassine, Rafik Zouari, Adel Khedher, Narjess Khalfallah, Taieb Ben Abdallah and Yousr Gorgi

    Citation: Biomarker Research 2013 1:20

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  10. Content type: Research

    Accumulated data from previous studies appear to suggest a link between the overexpression of a 35 kDa fragment of serum inter-alpha-trypsin inhibitor H4 (ITIH4) with cancers that are associated with up-regula...

    Authors: Emida Mohamed, Jaime Jacqueline Jayapalan, Puteri Shafinaz Abdul-Rahman, Siti Zawiah Omar and Onn Haji Hashim

    Citation: Biomarker Research 2013 1:19

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  11. Content type: Short report

    Nipple aspirate fluid (NAF) contains large amounts of protein thought to reflect the microenvironment of the breast, and is of interest in breast cancer prevention research. The correlation between specific NA...

    Authors: Jessica A Miller, Patricia A Thompson, Iman A Hakim, Ana Maria Lopez, Cynthia A Thomson, Chiu-Hsieh Hsu and H-H Sherry Chow

    Citation: Biomarker Research 2013 1:18

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  12. Content type: Review

    Insulin resistance associated with type 2 diabetes mellitus (T2DM), obesity, and atherosclerosis is a global health problem. A portfolio of abnormalities of metabolic and vascular homeostasis accompanies T2DM ...

    Authors: Fuyong Du, Anthony Virtue, Hong Wang and Xiao-Feng Yang

    Citation: Biomarker Research 2013 1:17

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  13. Content type: Research

    Colorectal cancer remains one of the leading causes of death from cancer in industrialized countries. Integrins are a family of heterodimeric glycoproteins involved in bidirectional cell signaling and particip...

    Authors: Salah Boudjadi, Julie C Carrier and Jean-François Beaulieu

    Citation: Biomarker Research 2013 1:16

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  14. Content type: Short report

    The cyclin-dependent kinase inhibitor p27Kip1 functions during normal cerebellar development and has demonstrated tumor suppressor functions in mouse models of medulloblastoma. Because P27 loss is associated with...

    Authors: Beryl A Hatton, David W Ellison, Amar Gajjar, Marcel Kool, Matthew Fero and James M Olson

    Citation: Biomarker Research 2013 1:14

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  15. Content type: Research

    IK is a nuclear protein containing a unique domain named RED due to the presence of a repetitive arginine (R), aspartic (E), and glutamic acid (D) sequence. To date, the function of this protein remains largel...

    Authors: Liyan Hu, Feikun Yang, Xianan Liu, Dazhong Xu and Wei Dai

    Citation: Biomarker Research 2013 1:11

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  16. Content type: Research

    Endometrial cancer (EC) is the leading malignant tumor occurring in the female genital tract and some subtypes are highly invasive and metastatic. miRNAs are small non-coding RNAs that have a broad impact on c...

    Authors: Haiyan Zhai, Mihriban Karaayvaz, Peixin Dong, Noriaki Sakuragi and Jingfang Ju

    Citation: Biomarker Research 2013 1:12

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  17. Content type: Review

    Diabetic kidney disease is the leading cause of end-stage renal disease in developed and developing countries. Microalbuminuria is the gold standard for detection and prediction of diabetic kidney disease and ...

    Authors: Cheng Wang, CuiCui Li, WenYu Gong and Tanqi Lou

    Citation: Biomarker Research 2013 1:9

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  18. Content type: Research

    Metabolic alteration is one of the hallmarks of carcinogenesis. We aimed to identify certain metabolic biomarkers for the early detection of pancreatic cancer (PC) using the transgenic PTEN-null mouse model. P...

    Authors: He N Xu, Shoko Nioka and Lin Z Li

    Citation: Biomarker Research 2013 1:6

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  19. Content type: Review

    Despite several decades of intensive effort to improve the imaging techniques for lung cancer diagnosis and treatment, primary lung cancer is still the number one cause of cancer death in the United States and...

    Authors: Dong Xiang, Bicheng Zhang, Donald Doll, Kui Shen, Goetz Kloecker and Carl Freter

    Citation: Biomarker Research 2013 1:4

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2017 Journal Metrics

  • Speed
    33 days to first decision for reviewed manuscripts only
    30 days to first decision for all manuscripts
    76 days from submission to acceptance
    12 days from acceptance to publication

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