Karter AJ, Schillinger D, Adams AS, Moffet HH, Liu J, Adler NE, et al. Elevated rates of diabetes in Pacific Islanders and Asian subgroups: The Diabetes Study of Northern California (DISTANCE). Diabetes Care. 2013;36(3):574–9. doi:10.2337/dc12-0722.
Kanaya AM, Herrington D, Vittinghoff E, Ewing SK, Liu K, Blaha MJ, et al. Understanding the high prevalence of diabetes in U.S. south Asians compared with four racial/ethnic groups: the MASALA and MESA studies. Diabetes Care. 2014;37(6):1621–8. doi:10.2337/dc13-2656.
Kozomara A, Griffiths-Jones S. miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 2011;39(Database issue):D152–7. doi:10.1093/nar/gkq1027.
Kozomara A, Griffiths-Jones S. miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 2011;39(Database issue):D152–7. doi:10.1093/nar/gkq1027.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ortega FJ, Mercader JM, Moreno-Navarrete JM, Rovira O, Guerra E, Esteve E, et al. Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization. Diabetes Care. 2014;37:1375–83. doi:10.2337/dc13-1847.
Pescador N, Perez-Barba M, Ibarra JM, Corbaton A, Martinez-Larrad MT, Serrano-Rios M. Serum Circulating microRNA Profiling for Identification of Potential Type 2 Diabetes and Obesity Biomarkers. PLoS One. 2013;8(10):e77251. doi:10.1371/journal.pone.0077251.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wang X, Sundquist J, Zoller B, Memon AA, Palmer K, Sundquist K, et al. Determination of 14 Circulating microRNAs in Swedes and Iraqis with and without Diabetes Mellitus Type 2. PLoS One. 2014;9(1):e86792. doi:10.1371/journal.pone.0086792.
Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, Prokopi M, et al. Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res. 2010;107(6):810–7. doi:10.1161/CIRCRESAHA.110.226357.
Liu Y, Gao G, Yang C, Zhou K, Shen B, Liang H, et al. The Role of Circulating MicroRNA-126 (miR-126): A Novel Biomarker for Screening Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus. Int J Mol Sci. 2014;15(6):10567–77. doi:10.3390/ijms150610567.
Wang YT, Tsai PC, Liao YC, Hsu CY, Juo SH. Circulating microRNAs have a sex-specific association with metabolic syndrome. J Biomed Sci. 2013;20:72. doi:10.1186/1423-0127-20-72.
Article
PubMed Central
PubMed
Google Scholar
Zhu H, Leung SW. Identification of microRNA biomarkers in type 2 diabetes: a meta-analysis of controlled profiling studies. Diabetologia. 2015;58(5):900–11. doi:10.1007/s00125-015-3510-2.
Article
CAS
PubMed
Google Scholar
Higuchi C, Nakatsuka A, Eguchi J, Teshigawara S, Kanzaki M, Katayama A, et al. Identification of Circulating miR-101, miR-375 and miR-802 as Biomarkers for Type 2 Diabetes. Metabolism. 2015;64(4):489–97. doi:10.1016/j.metabol.2014.12.003.
Kanaya AM, Wassel CL, Mathur D, Stewart A, Herrington D, Budoff MJ, et al. Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis. Metab Syndr Relat Disord. 2010;8(2):157–64. doi:10.1089/met.2009.0062.
Misra R, Patel T, Kotha P, Raji A, Ganda O, Banerji M, et al. Prevalence of diabetes, metabolic syndrome, and cardiovascular risk factors in US Asian Indians: results from a national study. J Diabetes Complications. 2009. doi:10.1016/j.jdiacomp.2009.01.003.
Federation ID. IDF Diabetes Atlas. Internaional Diabetes Federation, Brussels, Belgium. 2013. http://www.idf.org/diabetesatlas. Accessed March 5 2015.
Gujral UP, Narayan KM, Pradeepa RG, Deepa M, Ali MK, Anjana RM, et al. Comparing Type 2 Diabetes, Prediabetes, and Their Associated Risk Factors in Asian Indians in India and in the U.S.: The CARRS and MASALA Studies. Diabetes Care. 2015;38(7):1312–8. doi:10.2337/dc15-0032.
Flowers E, Aouizerat BE, Abbasi F, Lamendola C, Grove KM, Fukuoka Y et al. Circulating microRNA-320a and microRNA-486 predict thiazolidinedione response: Moving towards precision health for diabetes prevention. Metabolism. 2015. doi:10.1016/j.metabol.2015.05.013
Small EM, O'Rourke JR, Moresi V, Sutherland LB, McAnally J, Gerard RD, et al. Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486. Proc Natl Acad Sci U S A. 2010;107(9):4218–23. doi:10.1073/pnas.1000300107.
Xu J, Li R, Workeneh B, Dong Y, Wang X, Hu Z. Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486. Kidney Int. 2012;82(4):401–11. doi:10.1038/ki.2012.84.
Article
PubMed Central
CAS
PubMed
Google Scholar
Butler M, McKay RA, Popoff IJ, Gaarde WA, Witchell D, Murray SF, et al. Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice. Diabetes. 2002;51(4):1028–34.
Pal A, Barber TM, Van de Bunt M, Rudge SA, Zhang Q, Lachlan KL, et al. PTEN mutations as a cause of constitutive insulin sensitivity and obesity. N Engl J Med. 2012;367(11):1002–11. doi:10.1056/NEJMoa1113966.
Tamguney T, Stokoe D. New insights into PTEN. J Cell Sci. 2007;120(Pt 23):4071–9. doi:10.1242/jcs.015230.
Article
CAS
PubMed
Google Scholar
Peng Y, Dai Y, Hitchcock C, Yang X, Kassis ES, Liu L, et al. Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer. Proc Natl Acad Sci U S A. 2013;110(37):15043–8. doi:10.1073/pnas.1307107110.
Huang XP, Hou J, Shen XY, Huang CY, Zhang XH, Xie YA, et al. MicroRNA-486-5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1. FEBS J. 2015;282(3):579–94. doi:10.1111/febs.13167.
Sun H, Cui C, Xiao F, Wang H, Xu J, Shi X et al. MiR-486 regulates metastasis and chemosensitivity in hepatocellular carcinoma by targeting CLDN10 and CITRON. Hepatology research : the official journal of the Japan Society of Hepatology. 2015. doi:10.1111/hepr.12500
Song K, Han C, Zhang J, Lu D, Dash S, Feitelson M, et al. Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells. Hepatology. 2013;58(5):1681–92. doi:10.1002/hep.26514.
Coulouarn C, Factor VM, Andersen JB, Durkin ME, Thorgeirsson SS. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene. 2009;28(40):3526–36. doi:10.1038/onc.2009.211.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hu J, Xu Y, Hao J, Wang S, Li C, Meng S. MiR-122 in hepatic function and liver diseases. Protein Cell. 2012;3(5):364–71. doi:10.1007/s13238-012-2036-3.
Article
CAS
PubMed
Google Scholar
Jopling C. Liver-specific microRNA-122: Biogenesis and function. RNA Biol. 2012;9(2):137–42. doi:10.4161/rna.18827.
Article
PubMed Central
CAS
PubMed
Google Scholar
Flowers E, Froelicher ES, Aouizerat BE. MicroRNA regulation of lipid metabolism. Metabolism. 2013;62(1):12–20. doi:10.1016/j.metabol.2012.04.009.
Article
PubMed Central
CAS
PubMed
Google Scholar
Flowers E, Singh K, Molina C, Mathur A, Aouizerat BE. MicroRNA associated with atherogenic dyslipidemia in South Asian men. Int J Cardiol. 2013;168(5):4884–5. doi:10.1016/j.ijcard.2013.07.029.
Article
PubMed
Google Scholar
Sun LL, Jiang BG, Li WT, Zou JJ, Shi YQ, Liu ZM. MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expression. Diabetes Res Clin Pract. 2011;91(1):94–100. doi:10.1016/j.diabres.2010.11.006.
Article
CAS
PubMed
Google Scholar
Liu LF, Liang Z, Lv ZR, Liu XH, Bai J, Chen J, et al. MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. J Geriatr Cardiol. 2012;9(1):28–32. doi:10.3724/sp.j.1263.2012.00028.
Spinetti G, Fortunato O, Caporali A, Shantikumar S, Marchetti M, Meloni M, et al. MicroRNA-15a and microRNA-16 impair human circulating proangiogenic cell functions and are increased in the proangiogenic cells and serum of patients with critical limb ischemia. Circ Res. 2013;112(2):335–46. doi:10.1161/circresaha.111.300418.
Yin KJ, Deng Z, Hamblin M, Xiang Y, Huang H, Zhang J, et al. Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury. J Neurosci. 2010;30(18):6398–408. doi:10.1523/jneurosci.0780-10.2010.
Yin KJ, Olsen K, Hamblin M, Zhang J, Schwendeman SP, Chen YE. Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia. J Biol Chem. 2012;287(32):27055–64. doi:10.1074/jbc.M112.364414.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lin J, Huang S, Wu S, Ding J, Zhao Y, Liang L, et al. MicroRNA-423 promotes cell growth and regulates G(1)/S transition by targeting p21Cip1/Waf1 in hepatocellular carcinoma. Carcinogenesis. 2011;32(11):1641–7. doi:10.1093/carcin/bgr199.
Guo T, Feng Y, Liu Q, Yang X, Jiang T, Chen Y, et al. MicroRNA-320a suppresses in GBM patients and modulates glioma cell functions by targeting IGF-1R. Tumour Biol. 2014;35(11):11269–75. doi:10.1007/s13277-014-2283-4.
Qi X, Li J, Zhou C, Lv C, Tian M. MicroRNA-320a inhibits cell proliferation, migration and invasion by targeting BMI-1 in nasopharyngeal carcinoma. FEBS Lett. 2014;588(20):3732–8. doi:10.1016/j.febslet.2014.08.021.
Article
CAS
PubMed
Google Scholar
Schrottmaier WC, Oskolkova OV, Schabbauer G, Afonyushkin T. MicroRNA miR-320a modulates induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells. Atherosclerosis. 2014;235(1):1–8. doi:10.1016/j.atherosclerosis.2014.03.026.
Article
CAS
PubMed
Google Scholar
Tang H, Lee M, Sharpe O, Salamone L, Noonan EJ, Hoang CD, et al. Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB J. 2012;26(11):4710–21. doi:10.1096/fj.11-197467.
Wong N, Wang X. miRDB: an online resource for microRNA target prediction and functional annotations. Nucleic Acids Res. 2015;43(Database issue):D146–52. doi:10.1093/nar/gku1104.
Article
PubMed Central
PubMed
Google Scholar
Lagana A, Forte S, Giudice A, Arena MR, Puglisi PL, Giugno R et al. miRo: a miRNA knowledge base. Database : the journal of biological databases and curation. 2009;2009:bap008. doi:10.1093/database/bap008.
Farina NH, Wood ME, Perrapato SD, Francklyn CS, Stein GS, Stein JL, et al. Standardizing Analysis of Circulating MicroRNA: Clinical and Biological Relevance. J Cell Biochem. 2013;115:805–11. doi:10.1002/jcb.24745.
Mestdagh P, Van Vlierberghe P, De Weer A, Muth D, Westermann F, Speleman F, et al. A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol. 2009;10(6):R64. doi:10.1186/gb-2009-10-6-r64.
Meyer SU, Kaiser S, Wagner C, Thirion C, Pfaffl MW. Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs--a comparative study. PLoS One. 2012;7(6):e38946. doi:10.1371/journal.pone.0038946.
Article
PubMed Central
CAS
PubMed
Google Scholar
Qureshi R, Sacan A. A novel method for the normalization of microRNA RT-PCR data. BMC Med Genet. 2013;6 Suppl 1:S14. doi:10.1186/1755-8794-6-S1-S14.
Google Scholar
Kumarswamy R, Volkmann I, Jazbutyte V, Dangwal S, Park DH, Thum T. Transforming growth factor-beta-induced endothelial-to-mesenchymal transition is partly mediated by microRNA-21. Arterioscler Thromb Vasc Biol. 2012;32(2):361–9. doi:10.1161/ATVBAHA.111.234286.
Article
CAS
PubMed
Google Scholar
Ainsworth BE, Irwin ML, Addy CL, Whitt MC, Stolarczyk LM. Moderate physical activity patterns of minority women: the Cross-Cultural Activity Participation Study. J Womens Health Gend Based Med. 1999;8(6):805–13. doi:10.1089/152460999319129.
Article
CAS
PubMed
Google Scholar
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–9.
Article
CAS
PubMed
Google Scholar
Chapin SC, Appleyard DC, Pregibon DC, Doyle PS. Rapid microRNA profiling on encoded gel microparticles. Angew Chem Int Ed Engl. 2011;50(10):2289–93. doi:10.1002/anie.201006523.
Article
PubMed Central
CAS
PubMed
Google Scholar
Firefly Bioworks, Inc. http://fireflybio.com/sites/default/files/Documentation/TechNotes/Pregibon_miRNAProfiling_2012.pdf. Accessed July 14 2015.
Le MT, Hamar P, Guo C, Basar E, Perdigao-Henriques R, Balaj L, et al. miR-200-containing extracellular vesicles promote breast cancer cell metastasis. J Clin Invest. 2014;124(12):5109–28. doi:10.1172/jci75695.
Hoss AG, Labadorf A, Latourelle JC, Kartha VK, Hadzi TC, Gusella JF, et al. miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement. BMC Med Genet. 2015;8(1):10. doi:10.1186/s12920-015-0083-3.
Ren Z, Ambros VR. Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A. 2015;112(18):E2366–75. doi:10.1073/pnas.1422858112.
Article
PubMed Central
CAS
PubMed
Google Scholar