Chuong CM, Nickoloff BJ, Elias PM, Goldsmith LA, Macher E, Maderson PA, Sundberg JP, Tagami H, Plonka PM, Thestrup-Pederson K, Bernard BA, Schroder JM, Dotto P, Chang CM, Williams ML, Feingold KR, King LE, Kligman AM, Rees JL, Christophers E: What is the ‘true’ function of skin? Exp Dermatol 2002, 11: 159–187.
Article
CAS
PubMed
Google Scholar
Ghosh AK: Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood) 2002, 227: 301–314.
CAS
Google Scholar
Uitto J, Olsen DR, Fazio MJ: Extracellular matrix of the skin: 50 years of progress. J Invest Dermatol 1989, 92: 61S-77S.
CAS
PubMed
Google Scholar
Bowden PE, Wood EJ, Cunliffe WJ: Comparison of prekeratin and keratin polypeptides in normal and psoriatic human epidermis. Biochim Biophys Acta 1983, 743: 172–179. 10.1016/0167-4838(83)90431-4
Article
CAS
PubMed
Google Scholar
Sun TT, Eichner R, Nelson WG, Vidrich A, Woodcock-Mitchell J: Keratin expression during normal epidermal differentiation. Curr Probl Dermatol 1983, 11: 277–291.
Article
CAS
PubMed
Google Scholar
Woodcock-Mitchell J, Eichner R, Nelson WG, Sun TT: Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol 1982, 95: 580–588. 10.1083/jcb.95.2.580
Article
CAS
PubMed
Google Scholar
Portugal-Cohen M, Horev L, Ruffer C, Schlippe G, Voss W, Ma’or Z, Oron M, Soroka Y, Frusic-Zlotkin M, Milner Y, Kohen R: Non-invasive skin biomarkers quantification of psoriasis and atopic dermatitis: cytokines, antioxidants and psoriatic skin auto-fluorescence. Biomed Pharmacother 2012, 66: 293–299. 10.1016/j.biopha.2011.12.009
Article
CAS
PubMed
Google Scholar
Bose F, Petti L, Diani M, Moscheni C, Molteni S, Altomare A, Rossi RL, Talarico D, Fontana R, Russo V, Altomare G, Reali E: Inhibition of CCR7/CCL19 axis in lesional skin is a critical event for clinical remission induced by TNF blockade in patients with psoriasis. Am J Pathol 2013, 183: 413–421. 10.1016/j.ajpath.2013.04.021
Article
CAS
PubMed
Google Scholar
Mee JB, Corkm MJ, di Giovine FS, Duff GW, Groves RW: Interleukin-1: a key inflammatory mediator in psoriasis? Cytokine 2006, 33: 72–78. 10.1016/j.cyto.2005.12.001
Article
CAS
PubMed
Google Scholar
Kristensen M, Deleuran B, Eedy DJ, Feldmann M, Breathnach SM, Brennan FM: Distribution of interleukin 1 receptor antagonist protein (IRAP), interleukin 1 receptor, and interleukin 1 alpha in normal and psoriatic skin: decreased expression of IRAP in psoriatic lesional epidermis. Br J Dermatol 1992, 127: 305–311. 10.1111/j.1365-2133.1992.tb00446.x
Article
CAS
PubMed
Google Scholar
Hammerberg C, Arend WP, Fisher GJ, Chan LS, Berger AE, Haskill JS, Voorhees JJ, Cooper KD: Interleukin-1 receptor antagonist in normal and psoriatic epidermis. J Clin Invest 1992, 90: 571–583. 10.1172/JCI115896
Article
CAS
PubMed Central
PubMed
Google Scholar
Cooper KD, Hammerberg C, Baadsgaard O, Elder JT, Chan LS, Sauder DN, Voorhees JJ, Fisher G: IL-1 activity is reduced in psoriatic skin: decreased IL-1 alpha and increased nonfunctional IL-1 beta. J Immunol 1990, 144: 4593–4603.
CAS
PubMed
Google Scholar
McCully ML, Ladell K, Hakobyan S, Mansel RE, Price DA, Moser B: Epidermis instructs skin homing receptor expression in human T cells. Blood 2012, 120: 4591–4598. 10.1182/blood-2012-05-433037
Article
CAS
PubMed Central
PubMed
Google Scholar
Schaerli P, Ebert L, Willimann K, Blaser A, Roos RS, Loetscher P, Moser B: A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med 2004, 199: 1265–1275. 10.1084/jem.20032177
Article
CAS
PubMed Central
PubMed
Google Scholar
Weninger W, Uthman A, Pammer J, Pichler A, Ballaun C, Lang IM, Plettenberg A, Bankl HC, Sturzl M, Tschachler E: Vascular endothelial growth factor production in normal epidermis and in benign and malignant epithelial skin tumors. Lab Invest 1996, 75: 647–657.
CAS
PubMed
Google Scholar
Viac J, Palacio S, Schmitt D, Claudy A: Expression of vascular endothelial growth factor in normal epidermis, epithelial tumors and cultured keratinocytes. Arch Dermatol Res 1997, 289: 158–163. 10.1007/s004030050172
Article
CAS
PubMed
Google Scholar
Detmar M: The role of VEGF and thrombospondins in skin angiogenesis. J Dermatol Sci 2000,24(Suppl):S78-S84.
Article
CAS
PubMed
Google Scholar
Ali RS, Falconer A, Ikram M, Bissett CE, Cerio R, Quinn AG: Expression of the peptide antibiotics human beta defensin-1 and human beta defensin-2 in normal human skin. J Invest Dermatol 2001, 117: 106–111. 10.1046/j.0022-202x.2001.01401.x
Article
CAS
PubMed
Google Scholar
Schmitt J, Langan S, Deckert S, Svensson A, von Kobyletzki L, Thomas K, Spuls P: Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. J Allergy Clin Immunol 2013, 132: 1337–1347. 10.1016/j.jaci.2013.07.008
Article
PubMed
Google Scholar
Oranje AP, Glazenburg EJ, Wolkerstorfer A, de Waard-van der Spek FB: Practical issues on interpretation of scoring atopic dermatitis: the SCORAD index, objective SCORAD and the three-item severity score. Br J Dermatol 2007, 157: 645–648. 10.1111/j.1365-2133.2007.08112.x
Article
CAS
PubMed
Google Scholar
Schmitt J, Wozel G: The psoriasis area and severity index is the adequate criterion to define severity in chronic plaque-type psoriasis. Dermatology 2005, 210: 194–199. 10.1159/000083509
Article
PubMed
Google Scholar
Sandby-Moller J, Wulf HC: Ultrasonographic subepidermal low-echogenic band, dependence of age and body site. Skin Res Technol 2004, 10: 57–63. 10.1111/j.1600-0846.2004.00056.x
Article
PubMed
Google Scholar
El-Zawahry MB, Abdel El-Hameed El-Cheweikh HM, Abd-El-Rahman S, Ahmed Bassiouny D, Mohamed Fawzy M: Ultrasound biomicroscopy in the diagnosis of skin diseases. Eur J Dermatol 2007, 17: 469–475.
PubMed
Google Scholar
Biomarkers Definitions Working Group: Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001, 69: 89–95.
Article
Google Scholar
Malaviya R, Sun Y, Tan JK, Magliocco M, Gottlieb AB: Induction of lesional and circulating leukocyte apoptosis by infliximab in a patient with moderate to severe psoriasis. J Drugs Dermatol 2006, 9: 890–893.
Google Scholar
Frank R, Hargreaves R: Clinical biomarkers in drug discovery and development. Nat Rev Drug Discov 2003, 2: 566–580. 10.1038/nrd1130
Article
CAS
PubMed
Google Scholar
Leigh IM, Navsaria H, Purkis PE, McKay IA, Bowden PE, Riddle PN: Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br J Dermatol 1995, 133: 501–511. 10.1111/j.1365-2133.1995.tb02696.x
Article
CAS
PubMed
Google Scholar
Bhawan J, Bansal C, Whren K, Schwertschlag U: K16 expression in uninvolved psoriatic skin: a possible marker of pre-clinical psoriasis. J Cutan Pathol 2004, 31: 471–476. 10.1111/j.0303-6987.2004.0220.x
Article
PubMed
Google Scholar
Donetti E, Gualerzi A, Ricceri F, Pescitelli L, Bedoni M, Prignano F: Etanercept restores a differentiated keratinocyte phenotype in psoriatic human skin: a morphological study. Exp Dermatol 2012, 21: 549–551. 10.1111/j.1600-0625.2012.01518.x
Article
CAS
PubMed
Google Scholar
Wilson CL, Dean D, Lane BE, Dawber PR, Leigh IM: Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins. Br J Dermatol 1994, 131: 191–200.
Article
CAS
PubMed
Google Scholar
Lemster BH, Carroll PB, Rilo HR, Johnson N, Nikaein A, Thomson AW: IL-8/IL-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy. Clin Exp Immunol 1995, 99: 148–154.
Article
CAS
PubMed Central
PubMed
Google Scholar
Caldarola G, De Simone C, Carbone A, Tulli A, Amerio P, Feliciani C: TNFalpha and its receptors in psoriatic skin, before and after treatment with etanercept. Int J Immunopathol Pharmacol 2009, 22: 961–966.
CAS
PubMed
Google Scholar
Rashmi R, Rao KS, Basavaraj KH: A comprehensive review of biomarkers in psoriasis. Clin Exp Dermatol 2009, 34: 658–663. 10.1111/j.1365-2230.2009.03410.x
Article
CAS
PubMed
Google Scholar
Li J, Chen X, Liu Z, Yue Q, Liu H: Expression of Th17 cytokines in skin lesions of patients with psoriasis. J Huazhong Univ Sci Technolog Med Sci 2007, 27: 330–332. 10.1007/s11596-007-0329-1
Article
PubMed
CAS
Google Scholar
Zaba LC, Cardinale I, Gilleaudeau P, Sullivan-Whalen M, Suarez-Farinas M, Fuentes-Duculan J, Novitskaya I, Khatcherian A, Bluth MJ, Lowes MA, Krueger AJ: Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med 2007, 204: 3183–3194. 10.1084/jem.20071094
Article
CAS
PubMed Central
PubMed
Google Scholar
Antiga E, Volpi W, Chiarini C, Cardilicchia E, Fili L, Manuelli C, Parrochi P, Fabbri P, Caproni M: The role of etanercept on the expression of markers of T helper 17 cells and their precursors in skin lesions of patients with psoriasis vulgaris. Int J Immunopathol Pharmacol 2010, 23: 767–774.
CAS
PubMed
Google Scholar
Portugal-Cohen M, Kohen R: Non-invasive evaluation of skin cytokines secretion: an innovative complementary method for monitoring skin disorders. Methods 2013, 61: 63–68. 10.1016/j.ymeth.2012.10.002
Article
PubMed
CAS
Google Scholar
Portugal-Cohen M, Oron M, Ma’or Z, Boaz M, Shtendik L, Biro A, Cernes R, Barnea Z, Kazir Z, Kohen R: Noninvasive skin measurements to monitor chronic renal failure pathogenesis. Biomed Pharmacother 2011, 65: 280–285. 10.1016/j.biopha.2011.02.001
Article
CAS
PubMed
Google Scholar
Hendrix SW, Miller KH, Youket TE, Adam R, O’Connor RJ, Morel JG, Tepper BE: Optimization of the skin multiple analyte profile bioanalytical method for determination of skin biomarkers from D-Squame tape samples. Skin Res Technol 2007, 13: 330–342. 10.1111/j.1600-0846.2007.00235.x
Article
CAS
PubMed
Google Scholar
Perkins MA, Osterhues MA, Farage MA, Robinson MK: A noninvasive method to assess skin irritation and compromised skin conditions using simple tape adsorption of molecular markers of inflammation. Skin Res Technol 2001, 7: 227–237. 10.1034/j.1600-0846.2001.70405.x
Article
CAS
PubMed
Google Scholar
Perkins MA, Cardin CW, Osterhues MA, Robinson MK: A non-invasive tape absorption method for recovery of inflammatory mediators to differentiate normal from compromised scalp conditions. Skin Res Technol 2002, 8: 187–193. 10.1034/j.1600-0846.2002.20337.x
Article
CAS
PubMed
Google Scholar
Gillitzer R, Ritter U, Spandau U, Goebeler M, Brocker EB: Differential expression of GRO-alpha and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vivo. J Invest Dermatol 1996, 107: 778–782. 10.1111/1523-1747.ep12371803
Article
CAS
PubMed
Google Scholar
Kulke R, Todt-Pingel I, Rademacher D, Rowert J, Schroder JM, Christophers E: Co-localized overexpression of GRO-alpha and IL-8 mRNA is restricted to the suprapapillary layers of psoriatic lesions. J Invest Dermatol 1996, 106: 526–530. 10.1111/1523-1747.ep12343916
Article
CAS
PubMed
Google Scholar
Konig A, Krenn V, Toksoy A, Gerhard N, Gillitzer R: Mig, GRO alpha and RANTES messenger RNA expression in lining layer, infiltrates and different leucocyte populations of synovial tissue from patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis. Virchows Arch 2000, 436: 449–458. 10.1007/s004280050472
Article
CAS
PubMed
Google Scholar
Emson CL, Fitzmaurice S, Lindwall G, Li KW, Hellerstein MK, Maibach HI, Liao W, Turner SM: A pilot study demonstrating a non-invasive method for the measurement of protein turnover in skin disorders: application to psoriasis. Clin Transl Med 2013, 2: 12. 10.1186/2001-1326-2-12
Article
PubMed Central
PubMed
Google Scholar
Jones KD: Troubleshooting protein binding in nitrocellulose membranes, Part 1: Principles. IVD Technol 1999, 5: 32–41.
Google Scholar
Hirao T, Aoki H, Yoshida T, Sato Y, Kamoda H: Elevation of interleukin 1 receptor antagonist in the stratum corneum of sun-exposed and ultraviolet B-irradiated human skin. J Invest Dermatol 1996,106(5):1102–1107. 10.1111/1523-1747.ep12340143
Article
CAS
PubMed
Google Scholar