Skip to main content

Correction: Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia

The Original Article was published on 02 April 2022

Correction: Biomarker Res 10, 1-5 (2022)

https://doi.org/10.1186/s40364-022-00367-3

The original article [1] contained a typographical error in Fig 1F as well as some revision highlights in the supplementary material. These errors have since been corrected.

Fig. 1
figure 1

1,25 vitamin D induced FBP1 expression and reduced lactate production. A Pie distribution of RNA-seq FPKM-based gene expression in MV4–11 cells; B The FBP1 expression (FPKM) increased sharply from the low rank in non-treated (NO-TX) group to the high rank in 80 nM 1,25VD3-treated groups in different experimental groups of MV4–11, MOLM-14 cells, MV4–11-MIDO-R and MOLM-14-MIDO-R cells (MV4–11 or MOLM-14 resistant to midostaurin). MIDO: midostaurin (80 nM); C1–3 40x Images from Immunocytochemistry (ICC) to compare FBP1 protein before or after 1,25VD3 treatment; ICC control: 2nd antibody was applied without the primary antibody; D Representative FC plots showing the co-expression of FBP1 and VDR in 1,25VD3-treated MV4–11 cells; The Supplementary Figure 2 showing the FC plot of FITC-isotype control; E MV4–11 cells were treated with 80 nM 1,25VD3 for 48 h, then harvested and analyzed by RT-qPCR for expression of human FBP1 (Fold Change); F Treated MV4–11 cells were analyzed by WB for protein expression of human FBP1; G Treated MV4–11 cells were analyzed by Lactate Assay; Cumulative data of the concentration of intracellular lactate; Where applicable, data are means ± SEM and were analyzed by student “t” test. *p < 0.05, ***p < 0.005, n = 5

Reference

  1. Xu Y, et al. Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia. Biomarker Res. 2022;10:16. https://doi.org/10.1186/s40364-022-00367-3.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yi Xu.

Supplementary Information

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Xu, Y., Hino, C., Baylink, D.J. et al. Correction: Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia. Biomark Res 10, 33 (2022). https://doi.org/10.1186/s40364-022-00379-z

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s40364-022-00379-z