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Table 1 Some Properties of Proteins Investigated as Biomarkers for mTBI

From: Blood biomarkers for mild traumatic brain injury: a selective review of unresolved issues

Biomarker

MW†

Residues†

Role

Localization

Cell

S100B

10.7

92

regulatory

cytoplasm

astrocyte

UCH-L1

24.8

223

enzymatic

cytoplasm

neuron

tau isoform A§

32.9

316

structural

axon

neuron

tau isoform F§

45.8

441

structural

axon

neuron

GFAP

49.9

543

structural

cytoplasm

astrocyte

NF-L

61.5

304

structural

axon

neuron

  1. §Human CNS tau has 6 isoforms A-F [23].
  2. †Molecular weight (MW) in kDa, Residues is the number of amino acids [36]