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Table 4 Multinomial logistic regression of subclinical CVD markers and cluster membership

From: Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort

 

Cluster

RR ratio

95% CI

P value

MRI marker

    

End-diastolic volume in LV (ml)

1

0.557

0.391; 0.793

0.001

3

0.633

0.453; 0.886

0.008

End-systolic volume in LV (ml)

1

0.729

0.516; 1.029

0.072

3

0.921

0.678; 1.253

0.602

Stroke volume (ml)

1

0.528

0.368; 0.757

< 0.001

3

0.507

0.354; 0.727

< 0.001

Cardiac output of LV (ml/min)

1

0.742

0.563; 0.979

0.035

3

0.643

0.490; 0.842

0.001

Ejection fraction of LV (%)

1

1.009

0.725; 1.406

0.956

3

0.806

0.579; 1.122

0.201

Peak ejection rate (ml/s)

1

0.737

0.547; 0.995

0.046

3

0.740

0.546; 1.003

0.052

Cardiac mass, diastolic (g)

1

0.911

0.633; 1.312

0.617

3

0.884

0.608; 1.287

0.521

Cardiac mass, systolic (g)

1

0.976

0.656; 1.452

0.906

3

1.013

0.673; 1.526

0.950

Late Gadolinium Enhancement

1

0.720

0.165; 3.139

0.662

3

1.388

0.312; 6.17

0.667

Early diastolic filling rate (ml/s)

1

0.512

0.370; 0.708

< 0.001

3

0.589

0.434; 0.799

< 0.001

Late diastolic filling rate (ml/s)

1

0.998

0.73; 1.365

0.992

3

0.923

0.672; 1.268

0.621

All segments (mm/m2)

1

1.015

0.720; 1.432

0.931

3

1.033

0.724; 1.474

0.858

Basal segment (mm/m2)

1

1.036

0.746; 1.439

0.833

3

1.002

0.71; 1.412

0.993

Mid segment (mm/m2)

1

1.141

0.804; 1.618

0.460

3

1.161

0.807; 1.671

0.422

Apical segment (mm/m2)

1

0.834

0.604; 1.151

0.270

3

0.907

0.657; 1.252

0.552

Lateral segment (mm/m2)

1

0.929

0.672; 1.284

0.6560

3

0.856

0.614; 1.194

0.360

Septal segment (mm/m2)

1

1.143

0.801; 1.63

0.461

3

1.158

0.801; 1.676

0.435

Anterior segment (mm/m2)

1

0.982

0.696; 1.386

0.918

3

1.047

0.734; 1.491

0.801

Inferior segment (mm/m2)

1

1.040

0.744; 1.456

0.817

3

1.175

0.837; 1.65

0.350

Other markers

    

SCORE2

1

2.202

1.146;4.234

0.018

3

3.529

1.67; 7.455

0.001

Hypertension

1

2.152

1.02; 4.538

0.044

3

2.605

1.214; 5.593

0.014

Angina Pectoris

1

0.847

0.27; 2.657

0.776

3

0.298

0.083; 1.066

0.063

  1. All models were adjusted for age, sex, diabetes, systolic blood pressure, total cholesterol, and smoking status. CI = 95% confidence interval; RR = relative risk; LV = Left ventricle. Continuous exposures are scaled and relative risk ratios are given per standard deviation