Skip to main content
Fig. 1 | Biomarker Research

Fig. 1

From: RUNX1 promotes angiogenesis in colorectal cancer by regulating the crosstalk between tumor cells and tumor associated macrophages

Fig. 1

RUNX1 promotes TAMs infiltration in CRC. A Circular plot of immune cells enriched for the RUNX1-associated genes in COAD. RUNX1 expression is well related to M2 macrophage in COAD. B Correlation analysis between RUNX1 and IL-10 (left), CD206 (middle) and CD163 (right) in the TCGA database. C RT-qPCR analysis of the RUNX1 mRNA expression in tumor specimens and matched normal tissues (n = 66). D Correlation between the mRNA expression of RUNX1 and CD163, Arg1 in CRC tissues (n = 30). E Representative IHC analysis of RUNX1, CD68, CD163 and CCL2 expression in 12 pairs of cancer and the adjacent normal tissue from CRC patients. Scale bars: 100 μm. F Correlation between the expression of RUNX1 and CD68, CD163 in the IHC analysis. G Multi-label immunofluorescence staining of tumor tissue in patients with CRC. H The expression of RUNX1 in CRC tumor tissues and matched normal tissues was determined by western blotting (n = 24). I Multi-label immunofluorescence staining of tumor tissue from the nude mouse orthotopic CRC tumors

Back to article page

Biomarker Research

ISSN: 2050-7771

Contact us