Fig. 8
From: MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage
Schematic illustration of the most common microRNAs (miRNAs) studied in non-traumatic intracerebral hemorrhage (ICH) as therapeutic targets and non-invasive biomarkers. Notes: iNOS, Nitric oxide synthase; COX-2, Cyclooxygenase-2; MCP-1, Monocyte chemoattractant protein-1; IRAK1, Interleukin-1 receptor-associated kinase1; NFAT5, Nuclear factor of activated T cells 5; IL-6, Interleukin 6; TNF-a, Tumor necrosis factor alpha; IL‐1β, Interleukin 1 Beta; ZO-1, Zonula occludens-1; RAR-1, Protease activated receptor-1; TGF‑β1, Transforming growth factor β1; MDA, Malondialdehyde; SOD, Superoxide dismutase; GSH-Px, Glutathione peroxidase; TNF-α, Tumour necrosis factor alpha; MMP-9, Matrix metalloproteinase 9; PI3K, Phosphoinositide 3-kinases; Akt, RAC-alpha serine/threonine-protein kinase; VCAM-1, Vascular cell adhesion molecule 1; PIK3R2, Phosphatidylinositol 3-kinase regulatory subunit beta; TRAF6, TNF receptor associated factor 6; NF-κB, Nuclear factor kappa-light-chain-enhancer of activated B cells; ZEB1, Zinc finger E-box binding homeobox 1; GFAP, Glial fibrillary acidic protein; MTF1, Metal regulatory transcription factor 1; VEGF-A, Vascular endothelial growth factor A