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Table 8 Selected first-line results from phase 1/2 trials in RET rearranged NSCLC

From: Oncogenic alterations in advanced NSCLC: a molecular super-highway

Trial

Clinical trials ID

Treatments

Objective response rate (%)

Median progression-free survival (months)

Median overall survival (months)

Libretto-001

NCT03157128

Selpercatinib

85

16.5

NR

ARROW

NCT03037385

Praseltinib

70

17.1

NR