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Table 2 First-line phase 3 trials in EGFR exon 20 insertion NSCLC

From: Oncogenic alterations in advanced NSCLC: a molecular super-highway

Trial

Clinical trials ID

Treatments

Primary endpoint

PAPILLON

NCT04538664

Amivantamab with chemotherapy vs chemotherapy alone

PFS: endpoint met

EXCLAIM-2

NCT04129502

Mobocertinib vs chemotherapy

PFS: endpoint not met