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Fig. 3 | Biomarker Research

Fig. 3

From: MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma

Fig. 3

Performance of the RIB model in training and validation sets. a ROC curves of the RIB showed the favorable accuracy in four datasets. b Significant correlations were found between RIB score and absolute fraction of M2-like TAM. c RIB score in high- and low-M2 groups. d GSEA enrichment analysis showed more extensive immune responses in patients from high-M2 group. e GSEA enrichment analysis also showed more extensive immune responses in patients from high-M2RIB group. f Both of the estimated absolute fraction of M2-like TAM (left) and RIB score (right) had positive correlation with immune signatures characterized in hot tumors (eg immunescore) as well as negative correlation with tumor purity characterized in cold tumors. The block diagrams filled with white had no significant p values (p≥0.05), and the correlation coefficient (R) were embedded in each diagram

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Biomarker Research

ISSN: 2050-7771

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