Fig. 5

The combination of IN10018 and crizotinib promoted apoptosis in TNBC cells. A, B Representative flow cytometric plots of MDA-MB-231 and Hs578T cells. C, D Quantification of apoptosis rate of MDA-MB-231 and Hs578T cells. Q1: dead cells; Q2: late apoptosis; Q3: early apoptosis; Q4: living cells. E, F Western blotting assessment of cell apoptosis-related proteins in MDA-MB-231 and Hs578T cells. Data are represented as mean ± SEM. Significant levels: ns = not significant (P > 0.05), * P < 0.05, ** P < 0.01, and *** P < 0.001