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Fig. 11 | Biomarker Research

Fig. 11

From: Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling

Fig. 11

Ferroptosis induced by combining crizotinib with IN10018 was associated with p53. A Western blotting results of p53 downstream target proteins. B Fluorescence pictures of ROS. C Quantitative analysis of ROS fluorescence intensity. D ROS detection by Flow cytometry. E Quantitative analysis of ROS. F Measurement of lipid peroxidation using C11-BODIPY. G Quantitative analysis of lipid peroxidation using C11-BODIPY. H MDA content assay. I, J, K GSH and GSSG concentrations were determined using a GSH assay kit. L Western blotting results for ferroptosis-related proteins. Significant levels: ns = not significant (P > 0.05), * P < 0.05, ** P < 0.01, and *** P < 0.001

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Biomarker Research

ISSN: 2050-7771

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