Fig. 4
From: Phenotypic and metabolomic characteristics of mouse models of metabolic associated steatohepatitis
Lipoproteins as predominant metabolites in mouse models of diet-induced metabolic dysfunction-associated steatohepatitis. A Plot generated through principal component analysis (PCA) of the lipoproteins of mice fed with NC, HFD, WD, or HFC (16 and 32 weeks). B Plot generated through the PCA of the serological metabolites of mice fed with NC, HFD, WD, or HFC (16 and 32 weeks). PC1: principal component 1; PC2: principal component 2. Each point represents the metabolite profile of a biological replicate. C Heatmap exhibiting prominent differences in lipoprotein patterns among NC, 16-week experimental diet, and 32-week experimental diet. D Heatmap exhibiting no distinct pattern of serological metabolites. NC: normal chow; HFD: high-fat diet; WD: Western diet; and HFC: high-fat, high-cholesterol diet