Table 2 Hazard ratios of ECM level for cardiovascular events

Composite of CV events

 MMP-2

per 1 ng/mL

1.001 (1.000-1.002)

0.056

1.001 (1.000-1.002)

0.039

per SD

1.27 (1.02–1.59)

0.033

1.30 (1.04–1.63)

0.022

 MMP-9

per 1 ng/mL

1.002 (1.000-1.004)

0.107

1.002 (0.999–1.004)

0.152

per SD

1.12 (0.94–1.33)

0.203

1.12 (0.94–1.32)

0.199

 Tenascin-C

per 1 ng/mL

0.989 (0.953–1.027)

0.564

0.982 (0.940–1.026)

0.418

per SD

0.91 (0.64–1.31)

0.625

0.85 (0.57–1.27)

0.431

 Thrombospondin-2

per 1 ng/mL

0.998 (0.982–1.014)

0.799

0.998 (0.981–1.015)

0.822

per SD

0.99 (0.96–1.03)

0.754

1.00 (0.96–1.03)

0.776

Cardiac events

 MMP-2

per 1 ng/mL

1.002 (1.000-1.003)

0.009

1.002 (1.000-1.003)

0.007

per SD

1.40 (1.11–1.77)

0.004

1.43 (1.13–1.82)

0.003

 MMP-9

per 1 ng/mL

1.002 (1.000-1.005)

0.042

1.002 (1.000-1.005)

0.051

per SD

1.16 (0.97–1.38)

0.097

1.17 (0.98–1.38)

0.078

 Tenascin-C

per 1 ng/mL

0.983 (0.942–1.026)

0.443

0.973 (0.926–1.022)

0.278

per SD

0.85 (0.56–1.28)

0.435

0.78 (0.50–1.21)

0.262

 Thrombospondin-2

per 1 ng/mL

0.992 (0.974–1.010)

0.388

0.991 (0.972–1.010)

0.356

per SD

0.98 (0.94–1.02)

0.364

0.98 (0.94–1.02)

0.333