Biomarker Research

Table 1 Correlation between S100A8 expression and clinicopathological features of breast cancer patients in two TMAs (pooled data of BR2082a and HBreD145Su01)

From: S100A8/A9 as a risk factor for breast cancer negatively regulated by DACH1

Variables	n	S100A8 (High)	S100A8 (Low)	P value
Age				0.475^a
≥median	153	75	78
<median	141	75	66
Grade				0.039^b
3	8	5	3
2 + 2 ~ 3	193	107	86
1 + 1 ~ 2	36	12	24
Tumor size				0.188^a
T3-T4	31	19	12
Tis-T2	230	112	118
Lymph node				0.108^a
N+	124	56	68
N-	136	75	61
Stage				0.729^a
III	69	36	33
I–II	191	95	96
ER				< 0.0001^a
ER+	161	64	97
ER-	116	79	37
PR				< 0.0001^a
PR+	134	51	83
PR-	143	91	52
Her2				0.002^a
Her2+	37	31	6
Her2-	94	51	43

^aPearson chi-square test, ^bFisher’s exact test

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