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Fig. 2 | Biomarker Research

Fig. 2

From: Baseline extracellular vesicle miRNA-30c and autophagic CTCs predict chemoradiotherapy resistance and outcomes in patients with lung cancer

Fig. 2

Effects of miR-30c and EV miR-30c on viability and autophagy in NSCLC cells under radiotherapy and cisplatin treatment. A Relative viability of H1975 and A549 cells after treatment with radiotherapy or cisplatin in controls, cells treated with miR-30c mimic, and cells with miR-30c inhibitor and B their representative WB images including LC3B as biomarker for autophagy quantification and HSC70 as loading control. C Representative WB images of cells treated with plasmatic EVs loaded/ not loaded with miR-30c mimic from independents experiments including LC3B as biomarker for autophagy quantification and HSC70 as loading control. Graphs represent media of independent experiments and standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001

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