Table 1 Exosomes-related databases or tools

EVmiRNA

It provides sample information on miRNA expression profiles and EVs from different sources; miRNAs specifically expressed in different EVs as well as miRNA annotations including miRNA expression in EVs and the cancer genome atlas (TCGA) types; miRNA pathway regulations and miRNA functions.

http://bioinfo.life.hust.edu.cn/EVmiRNA

[39]

ExoCarta

It contains information about the tissue/cell types for isolating exosomes and functional studies of exosomes, including mass spectrometry, western blotting, biological pathways and protein-protein interaction (PPI) networks associated with exosomal proteins. Users can search by content types (RNA, protein, and lipid), species, tissue/cell types and genetic symbols.

http://www.exocarta.org

[40]

CMEP

It contains large-scale circulating miRNA datasets from different platforms, it provides miRNA expression profiles in exosomes, functional pathway enrichment analysis of miRNA target genes and feature selection methods.

http://syslab5.nchu.edu.tw/CMEP

[41]

exoRBase

It is the integration and visualization of RNA expression profiles based on RNA sequencing datas of exosomes derived from human body fluids, containing circRNA, lncRNA and mRNA data profiles, it provides annotations, expression levels and possible original tissues.

http://www.exoRBase.org

[42]

BoMiProt

It is a comprehensive database of bovine milk protein data containing information on exosomal protein function, biochemical properties, and post-translational modifications. In addition, users can search by milk fractions, post-translational modifications, and/or structures by filtering.

http://bomiprot.org

[43]

Xeno-miRNet

The aim is to search and explore heterologous exosomal miRNAs and their potential gene targets in different host species.

http://xeno.mirnet.ca

[44]

NONCODEv5

Construction of human lncRNA-disease and single nucleotide polymorphism-lncRNA-disease relationships; display of human exosomal lncRNA expression profiles; prediction of RNA secondary structures of non-coding human transcripts.

http://www.bioinfo.org/noncode/

[45]

miRandola

Inferring the potential biological functions of circulating miRNAs and their association with phenotypes.

http://atlas.dmi.unict.it/mirandola/index.html

[46]

Vesiclepedia

EVpedia

Manual searchable library of molecular data (lipids, RNA, and proteins) for Evs, including apoptotic bodies, exosomes, large dense core vesicles, microparticles and shedding microvesicles, also searchable by species, vesicles, and sample types.

It is a community web portal for EVs research, containing data on prokaryotic and eukaryotic EVs.

http://www.microvesicles.org

http://evpedia.info

[47]

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