Fig. 6

End motif sequences of ScfDNA in cancer vs. noncancer donors. (A) Volcano plot demonstrating 4-mer end motifs with significant differences in the ScfDNA reads. Multiple t test, without considering consistency of SD, false discovery rate Benjamini, Krieger and Yekutieli method, p value < 0.05, q-value < 0.05. (B) Heatmap demonstrating the top 20 significantly different 4-mer end motifs between cancer vs. noncancer, p value < 0.05, multiple t test, corrected FDR.