Table 4 Galectin-associated EV studies
From: Lectins as potential tools for cancer biomarker discovery from extracellular vesicles
Lectin | EV source | Separation method | Readout | Method | Ref |
|---|---|---|---|---|---|
Galectin-3 | Melanoma SK-Mel-5 cells | UC | Complex N-glycans mediate protein shorting to EVs | Lectin blotting | [161] |
Galectin-5 | Rat reticulocytes | UC | Galectin-5 has effect on EVs uptake by macrophages | Galectin blotting | [112] |
Galectin-3 | MDCK kidney cells | UC | Mechanism of galectin-3 delivery into ILVs for exosomes release | Galectin blotting | [156] |
Galectin-3 | Mice, C. neoformans strain, and patient serum | UC | Gal-3 inhibits fungal infection through direct antifungal effect | ELISA | [158] |
Galectin-3 | Mice, P. brasiliensis strain, and patient serum | UC | Gal-3 inhibits fungal growth through multiple mechanism | Galectin blotting | [159] |
Galectin-3 | Human semen | UC | Expression of gal-3 on human semen EVs | Galectin blotting | [155] |
Galectin-9 | Epstein-Barr virus (EBV)-infected NPC cells | UC and magnetic bead-based IA | EVs from EBV-infected tumor cells contain gal-9 protein | Galectin blotting | [160] |