Table 1 Baseline characteristics of patients with ARDS and control subjects
From: Prognostic value of secretory autophagosomes in patients with acute respiratory distress syndrome
Variables | ARDS (n = 46) | Controls (n = 8) | P value |
|---|---|---|---|
Age (year) | 58.50 [49.25-71.00] | 37.50 [31.50-48.75] | 0.005 |
Male, n (%) | 32 (69.6) | 8 (100.0) | 0.095 |
Cause of ARDS, n (%) | |||
• Direct ARDS • Indirect ARDS | 39 (84.8%) 7 (15.2%) | ||
Risk factor for ARDS, n (%) | |||
• Pneumonia • Sepsis • Pulmonary contusion • pancreatitis • Other | 27 (58.6%) 3 (6.5%) 9 (19.5%) 3 (6.5%) 4 (8.9) | ||
Comorbidities, n (%) | |||
• Diabetes | 5(10.9) | 0(0.0) | 1.000 |
• Hypertension | 18(39.1) | 4(50.0) | 0.702 |
• Cardiovascular disease | 7(15.2) | 0(0.0) | 0.540 |
• Cerebrovascular disease | 25(54.3) | 1(12.5) | 0.052 |
• Urinary system disease | 8(17.4) | 0(0.0) | 0.460 |
• Digestive system disease | 13(28.3) | 0(0.0) | 0.201 |
APACHE II score | 22.39 ± 7.15 | 6.50 ± 3.12 | < 0.001 |
SOFA score | 9.52 ± 3.66 | 1.5 ± 1.20 | < 0.001 |
Mechanical ventilation setting | |||
• Tidal volume (ml) | 400.00[342.50–420.00] | 450.00[427.50–460.00] | 0.001 |
• PEEP (cm H2O) | 10.00[6.75-12.00] | 5.00 | < 0.001 |
• PaO2/FiO2 (mm Hg) | 155.63 ± 63.03 | 321.43 ± 79.27 | < 0.001 |
Laboratory variables | |||
• Plasma creatinine (umoL/L) | 78.00[52.50–104.00] | 79.50[70.25-84.00] | 0.79 |
• White blood cell count (109/L) | 12.81[9.39–16.18] | 6.56[5.39–7.56] | 0.003 |
• Hemoglobin (g/L) | 91.86 ± 25.75 | 148.63 ± 9.38 | < 0.001 |
ICU stay (day) | 18.00[8.00–33.00] | 1 | < 0.001 |