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Fig. 1 | Biomarker Research

Fig. 1

From: Relevance of multilamellar and multicompartmental vesicles in biological fluids: understanding the significance of proportional variations and disease correlation

Fig. 1

Comparison between the image quality of cryo-TEM and conventional TEM in the same biological sample (egg yolk). Cryo-TEM reveals distinct types of extracellular vesicles (EVs). (A) Unilamellar vesicles, (B) Bilamellar vesicles with white arrows indicating the presence of multilamellar structures. (C) Multicompartmental vitellovesicles depicted by red arrows, where more than ten vesicles are packed inside a larger vesicle. (D) A multilamellar vesicle denoted by a green arrow. The scale bar is 200 nm for all panels except panel C is 100 nm. (E) Conventional TEM images show low resolution multicompartmental vesicle (yellow arrow), and (F) bicompartmental vesicles (blue arrows). It is well noted that the images quality are different and more advantages are towards the use of cryo-EM. These images have not been previously published

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Biomarker Research

ISSN: 2050-7771

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