Fig. 4
From: Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinoma
GRIN2D promoted tumor growth and liver metastasis in PDAC. (A). GRIN2D was knocked down by stable lentiviral shRNA system in SW1990 cells. (B). Knockdown of GRIN2D inhibited tumor growth in SW1990 cells. Photographs of mice xenograft at day 28 after knockdown of GRIN2D in SW1990 cells. (C). Tumor volume and tumor mass of xenograft mice after knockdown of GRIN2D. (D). IHC staining of Ki67, H&E Staining in mice subcutaneous tumors after knockdown of GRIN2D. (E). Knockdown of GRIN2D inhibited liver metastasis in SW1990 cells