Fig. 2From: Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinomaGRIN2D drove tumorigenic functions in PDAC cells. (A). GRIN2D was knocked down by siRNAs in SW1990 and PANC04.03 cells. (B). Knockdown of GRIN2D inhibited cell growth in PDAC cells. (C). Knockdown of GRIN2D inhibited colony formation in PDAC cells. (D). Knockdown of GRIN2D inhibited cell migration in PDAC cells. (E). Knockdown of GRIN2D inhibited cell invasion in PDAC cells. Cells in the colony formation assay and invasion assay were stained by crystal violet. Data are from at least three independent experiments. Mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001Back to article page