Fig. 3

Overexpression of SYT7 promotes CLL development in vitro. A qPCR and western blotting were used to verify the overexpression of SYT7 in MEC-2 cells. B CCK8 assay was used to verify the promoted cell proliferation by SYT7 overexpression. C Flow cytometry was performed to show the effects of SYT7 overexpression on CLL cell apoptosis. D Flow cytometry was performed to show the effects of SYT7 overexpression on CLL cell cycle distribution. E Transwell assay was utilized to display the effects of SYT7 overexpression on CLL cell migration (scale bar = 400 μm). Data were shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, based on a Student’s T-Test