Fig. 2

Knockdown of SYT7 inhibits CLL development in vitro. A qPCR and western blotting were used to verify the knockdown of SYT7 in MEC-2 and M01043 cells by shSYT7. B CCK8 assay was used to verify the inhibited cell proliferation by SYT7 knockdown. C Flow cytometry was performed to show the promoted cell apoptosis by SYT7 knockdown. D Flow cytometry was performed to show the arrest of cell cycle in G2 phase upon SYT7 knockdown. E Transwell assay was utilized to visualize the suppression of cell migration by SYT7 knockdown (scale bar = 400 μm). Data were shown as mean ± SD. **P < 0.01, ***P < 0.001, based on a Student’s T-Test