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Fig. 1 | Biomarker Research

Fig. 1

From: Single-cell technologies in multiple myeloma: new insights into disease pathogenesis and translational implications

Fig. 1

Unresolved questions in the field of myeloma biology research. Studying MM biology in both myeloma intrinsic and extrinsic contexts will advance understanding of how the complex cross-talk between myeloma cells and surrounding non-cancer cells results in the successful growth of malignant subclones, with impacts on clonal revolution and resistance to therapies. MM: multiple myeloma; MMSCs: multiple myeloma stem cells; TME: tumor microenvironment; BM: bone marrow

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