Fig. 3
From: Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential
Potential therapeutic strategies of targeting IGF2BPs in cancer. A The structure of small molecule inhibitors for IGF2BP1/2. B Oligonucleotide sequences designed according to IGF2BP1-RNA binding sites. C Natural plant extracts that effectively inhibit IGF2BP3 expression. d-ICD: derivative of isocorydine. D Torin1 (mTORC2 kinase inhibitor) and AZD0530 (Src kinase inhibitor) impede IGF2BP1-RNA interaction by hindering IGF2BP1 phosphorylation.