Fig. 2
From: Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential
The post-transcriptional regulatory mechanisms of IGF2BPs. A IGF2BPs with other RBPs (RNA-binding proteins) regulate mRNA stability, transport, and translation by recruiting cytoplasmic transcripts into protective mRNPs (messenger ribonucleoprotein particles) including PBs (processing bodies) and SGs (stress granules). B IGF2BPs function as m6A readers to promote their stabilization and translation by selectively recognizing m6A-modified mRNAs under stress conditions in SGs or under normal conditions in PBs.