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Table 1  Clinical and laboratory characteristics of the newly diagnosed (ND) AML patients

From: EIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p/RNF113A pathway

Characteristics

No. /treatments

Male/female

31/39

Age at study entry, year, median (range)

44(13-83)

Bone marrow blasts at diagnosis, %, median ( range)

85.5(28-98)

Peripheral Blood blasts at diagnosis, %, median ( range)

84.5(21-98)

WBC at diagnosis, ×109/L, median (median range)

16.13(1.21-89.17)

PLT at diagnosis, ×109/L, median (median range)

34.5(6-191)

HGB at diagnosis, g/L, median (median range)

81(51-135)

AML with minimal differentiation: M0

0

AML without maturation: M1

2

AML with maturation: M2

9

Acute Promyelocytic leukemia: M3

0

Acute Myelomonocytic leukemia: M4

23

Acute monoblastic or monocytic leukemia: M5

36

Acute erythroid leukemia: M6

0

Acute megakaryoblastic leukemia: M7

0

Preferred treatments

DA/IA (3+7)

  1. WBC white blood cell, PLT platelet, HGB hemoglobin, DA Daunorubicin+Cytarabine, IA idarubicin+Cytarabine