Fig. 3
From: Whole genome and RNA sequencing analyses for 254 Taiwanese hepatocellular carcinomas
Mutational signature on 254 Taiwanese HCCs. (A) Three signatures were extracted from 254 Taiwanese HCC and compared to COSMIC signatures catalogs, and the signature 1, 2 and 3 were correlated with SBS22 (aristolochic acid exposure), SBS5 and SBS9 respectively. Cluster with a cosine similarity of Taiwanese HCC resulting in three signatures and related case number. (B) Mutational signature and subgroup of HCCs: HBV infection, HCV infection, dual HBV and HCV infection, non-HBV/non-HCV, and double cancers