Fig. 5
From: Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis
Increased serum BMP8A levels in NASH patients with advanced fibrosis. A Serum levels of BMP8A determined by ELISA. Data are expressed as pg/ml and presented as mean ± SD. B Correlation in the study population of matched serum BMP8A levels with fibrosis stage. C AUROC of BMP8A univariate analysis to predict advanced fibrosis (F3-F4). D AUROC of multivariate analysis. Study population: 85 NASH patients, 52 with non or mild fibrosis (F0-F2) and 33 with advanced fibrosis (F3-F4), and 36 subjects with normal liver. NASH, nonalcoholic steatohepatitis. AUROC, area under the ROC curve. *p < 0.05, **p < 0.01 and ***p < 0.005, F3-4 vs. F0-2 or NL