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Table 2 The 7 DMRs for lung cancer diagnosis

From: Accurate detection of early-stage lung cancer using a panel of circulating cell-free DNA methylation biomarkers

Region

Gene symbol

Gene name

Feature type

chr17: 46,655,603–46,655,750

HOXB4

Homeobox protein Hox-B4

shore

chr17: 80,943,984–80,944,093

B3GNTL1

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1

opensea

chr19: 53,038,958–53,039,010

ZNF808

zinc finger protein 808

shore

chr2: 176,993,563–176,993,743

HOXD8

homeobox D8

island

chr2: 182,322,423–182,322,574

ITGA4

integrin subunit alpha 4

island

chr5: 40,681,077–40,681,250

PTGER4

prostaglandin E receptor 4

island

chr7: 27,195,684–27,195,794

HOXA7

homeobox A7

island