Fig. 3
From: BCL7A is silenced by hypermethylation to promote acute myeloid leukemia
RNA sequencing of wild-type BCL7A vs mutant BCL7A NB4 cell models. a Volcano plots highlighting the differentially expressed genes in NB4 cell line when comparing NB4 transfected with BCL7A wildtype and BCL7A mutant. b Enriched terms across the top significant (p adjusted) 400 differentially expressed genes when comparing NB4 transduced with wild-type BCL7A and BCL7A mutant. c Expression values according to our RNA-seq data of three selected genes: HMGCS1, IRF7, and H1-0. Log2 of variance-stabilized transformed (VST) gene counts was obtained with DESeq2 in R. The red horizontal lines represent the mean