Table 1 Characteristics of the 452 consecutive patients with community-acquired bloodstream infection included in the study

Age — N, median (IQR)

452

61 (31–74)

88

65 (55–78)

364

60 (22–72)

0.0002*

Male gender — n/N, % (95% CI)

274/452

60.6% (56.1–65.1)

54/88

61.4% (51.0–71.7)

220/364

60.4% (55.4–65.5)

0.90†

Procalcitonin (ng/mL) — N, median (IQR)

452

2.54 (0.60–11.75)

88

7.40 (1.94–19.88)

364

2.15 (0.490–10.57)

< 0.0001*

Sepsis at admission — n/N, % (95% CI)

92/452

20.4% (16.6–24.1)

16/88

18.2% (10.0–26.4)

76/364

20.9% (16.7–25.1)

0.57†

C-reactive protein (mg/L) — N, median (IQR)

326

138.9 (65.6–224.3)

59

166.5 (102.7–264.0)

267

130.0 (63.0–210.9)

0.006*

Lactates (mmol/L) — N, median (IQR)

203

1.7 (1.1–3.1)

54

2.5 (1.5–4.1)

149

1.6 (1.075–2.9)

0.002*

Cardiac troponin I (ng/mL) — N, median (IQR)

133

0.11 (0.04–0.43)

44

0.29 (0.07–1.80)

89

0.08 (0.04–0.23)

0.0003*

 Gram-positive

229/452

50.7% (46.0–55.3)

43/88

48.9% (38.2–59.5)

186/364

51.1% (45.9–56.3)

0.72†

 Gram-negative

203/452

44.9% (40.3–49.5)

41/88

46.6% (36.0–57.2)

162/364

44.5% (39.4–49.6)

0.72†

 Fungi

20/452

4.4% (2.5–6.3)

4/88

4.5% (0.1–8.9)

16/364

4.4% (2.28–6.5)

0.99†

 Staphylococcus aureus

123/452

27.2% (23.1–31.3)

29/88

33.0% (22.9–43.0)

94/364

25.8% (21.3–30.3)

0.18†

 Escherichia coli

117/452

25.9% (21.8–29.9)

20/88

22.7% (13.8–31.7)

97/364

26.6% (22.1–31.2)

0.45†

 Streptococcus spp.

76/452

16.8% (13.4–20.3)

6/88

6.8% (1.5–12.2)

70/364

19.2% (15.2–23.3)

0.005†

 Enterococcus spp.

30/452

6.6% (4.3–8.9)

8/88

9.1% (3–15.2)

22/364

6.0% (3.6–8.5)

0.30†

 Klebsiella spp.

29/452

6.4% (4.2–8.7)

10/88

11.4% (4.6–18.1)

19/364

5.2% (2.9–7.5)

0.04†

 Pseudomonas spp.

27/452

6.0% (3.8–8.2)

5/88

5.7% (0.7–10.6)

22/364

6.0% (3.6–8.5)

0.90†

 Fungi

20/452

4.4% (2.5–6.3)

4/88

4.6% (0.1–9.0)

16/364

4.4% (2.3–6.5)

0.95†

 Enterobacter spp.

15/452

3.3% (1.7–5)

5/88

5.7% (0.7–10.6)

10/364

2.8% (1.1–4.4)

0.17†

 Bacteroides spp.

7/452

1.6% (0.4–2.7)

1/88

1.1% (0–3.4)

6/364

1.7% (0.3–3.0)

—‡

 Acinetobacter spp.

5/452

1.1% (0.1–2.1)

0/88

0% (—)

5/364

1.4% (0.2–2.6)

—‡

 Citrobacter spp.

3/452

0.7% (0–1.4)

0/88

0% (—)

3/364

0.8% (0–1.8)

—‡