Table 2 Clinical characteristics of the NPC1 cohort
From: Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1
| Â | n | Mean | p-value* | Median (range) |
|---|---|---|---|---|
NPC NSS (points) | 28 | 16.8 ± 11.0 | - | 18.0 (0–42) |
No Miglustat | 14 | 20.0 ± 8.2 |  | 20.0 (0–32) |
Miglustat | 14 | 13.6 ± 12.8 | 0.07 | 13.6 (0–42) |
ASIS (points/year) | 26** | 1.95 ± 2.26 | - | 1.07 (0.31–9.37) |
No Miglustat | 13 | 2.25 ± 2.69 |  | 1.31 (0.31–9.37) |
Miglustat | 13 | 1.64 ± 1.80 | 0.61 | 0.89 (0.31–6.09) |
Age of Neurological Onset (years) | 28 | 8.47 ± 12.02 | - | 3.5 (1.3–43) |
No Miglustat | 14 | 12.07 ± 15.79 |  | 5.0 (1.5–43) |
Miglustat | 14 | 4.86 ± 4.79 | 0.23 | 2.0 (1.3–16) |