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Fig. 8 | Biomarker Research

Fig. 8

From: Circular RNA circEMB promotes osteosarcoma progression and metastasis by sponging miR-3184-5p and regulating EGFR expression

Fig. 8

The circEMB/miR-3184-5p/EGFR axis regulates the sensitivity of OSA cells to MTX. a circEMB expression was upregulated in MTX-resistant U2OS cells. b-g AutoDock Vina was used for the molecular docking of MTX and EGFR. h The IC50 of OSA cells treated with MTX. i-k Flow cytometric analysis of apoptosis and cell cycle distribution of MTX-resistant U2OS cells treated with MTX. Data are expressed as mean ± SD (n = 3) (*, p < 0.05; **, p < 0.01; ***, p < 0.001)

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Biomarker Research

ISSN: 2050-7771

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