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Fig. 2 | Biomarker Research

Fig. 2

From: Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation

Fig. 2

Functional effects of regulation of SLC25A21-AS1 in EOC cells. a Increased proliferation of EOC cells within 96 hours after knockdown of SLC25A21-AS1. ***P<0.001. Data represent mean ± SD (n = 3). b Reduced apoptosis of ovarian cancer cells after knockdown of SLC25A21-AS1. The effect on apoptosis compared through the number of early apoptotic process cells. Error bars are the mean ± SD of three independent replicate experiments. ***P<0.001. c The percentage of cells in G2 phase of ovarian cancer cells increased after knockdown of SLC25A21-AS1 (n=3). d. Knockdown of SLC25A21-AS1 can promote migration and invasion (n=3). The blue staining part is the positive count part. e Attenuated EOC cells proliferation within 96 hours after overexpression of SLC25A21-AS1. **P<0.01, *P<0.05. f Overexpression of SLC25A21-AS1 promotes apoptosis of EOC cells. Error bars values are all mean ± SD from three independent replicate experiments. g Overexpression of SLC25A21-AS1 decreased the percentage of cells in G2 phase (n=3). h Overexpression of SLC25A21-AS1 inhibited the migration and invasion of EOC cells (n=3)

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Biomarker Research

ISSN: 2050-7771

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