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Fig. 6 | Biomarker Research

Fig. 6

From: Loss of miR-637 promotes cancer cell stemness via WASH/IL-8 pathway and serves as a novel prognostic marker in esophageal squamous cell carcinoma

Fig. 6

Plasma miR-637 is a useful biomarker for the diagnosis and prognosis of ESCC patients. A, B The expression levels of miR-637 and IL-8 in the plasma of healthy donors (HD) and ESCC patients were examined by qRT-PCR (A) and ELISA (B), respectively. C The relationship between miR-637 and IL-8 expression in the plasma of ESCC patients was evaluated via Pearson correlation analysis. D, E Low expression levels of plasma miR-637 correlate with advanced TNM stage (D) and lymph node metastasis (E). F, G The prediction performance of plasma miR-637 (F) or plasma IL-8 (G) in a cohort of ESCC patients were determined by ROC analysis. Data are presented as mean ± standard deviation. ns, not significant; *p < 0.05, **p < 0.01, ***p < 0.001

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Biomarker Research

ISSN: 2050-7771

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