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Fig. 8 | Biomarker Research

Fig. 8

From: Competing endogenous RNA networks related to prognosis in chronic lymphocytic leukemia: comprehensive analyses and construction of a novel risk score model

Fig. 8

The mechanism of circRNA circ_0002078/miR-185-3p/TCF7L1 axis in CLL cells. The interaction mechanism between them is that circ_0002078 can absorb miR-185-3p like a sponge, thereby inhibiting the inhibitory effect of miR-185-3p on TCF7L1. This competitive combination leads to the increasing expression of TCF7L1, which contributes to the promotion of cell proliferation, metastasis and other life processes that can conducive to the development of cancer

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Biomarker Research

ISSN: 2050-7771

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