Fig. 7
From: Long noncoding RNA HOXC-AS3 interacts with CDK2 to promote proliferation in hepatocellular carcinoma
Schematic diagram of the mechanism by which HOXC-AS3 promotes HCC progression. HOXC-AS3 prevents P21 from binding to CDK2, resulting in CDK2 maintaining kinase activity, further phosphorylating RB, and promoting cell cycle from G1 to S-phase, which in turn leads to enhanced cell proliferation, and promoting the progression of HCC