Fig. 3

HOXC-AS3 promotes HCC cell proliferation in vivo. (A1) Representative images of subcutaneous xenograft tumors formation of the Vec group and HOXC-AS3 group. The dissected tumors from two groups were photographed. (A2) Representative images of subcutaneous xenograft tumors formation of the shNC group and Aso-2 group. The dissected tumors from two groups were photographed. (B1) Volumes and Weights of subcutaneous xenograft tumors in Vec group and HOXC-AS3 group. (B2) Volumes and Weights of subcutaneous xenograft tumors in shNC group and Aso-2 group. (C1) IHC staining Ki-67 expression of subcutaneous xenograft tumors in Vec group and HOXC-AS3 group. (C2) IHC staining Ki-67 expression of subcutaneous xenograft tumors in shNC group and Aso-2 group. (D1) Western blot show CDK2 expression of subcutaneous xenograft tumors in Vec group and HOXC-AS3 group. (D2) Western blot show CDK2 expression of subcutaneous xenograft tumors in shNC group and Aso-2 group. (E1) CDK2 levels measured by western blot and gray level in Vec group and HOXC-AS3 group. (E2) CDK2 levels measured by western blot and gray level in shNC group and Aso-2 group. (F1) Representative images of orthotopic xenograft tumors formation of the Vec group and HOXC-AS3 group. The dissected tumors from two groups were photographed. (F2) Representative images of orthotopic xenograft tumors formation of the shNC group and Aso-2 group. The dissected tumors from two groups were photographed. (G1) Sections of the Vec group and HOXC-AS3 group xenograft tumors stained with hematoxylin and eosin (H & E). (G2) Sections of the shNC group and Aso-2 group xenograft tumors stained with hematoxylin and eosin (H & E). (H1) Volumes of subcutaneous xenograft tumors in Vec group and HOXC-AS3 group. (H2) Volumes of subcutaneous xenograft tumors in shNC group and Aso-2 group. Data represent the MEAN ± S.E.M of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 (Student’s t test)