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Fig. 7 | Biomarker Research

Fig. 7

From: Selective isolation of extracellular vesicles from minimally processed human plasma as a translational strategy for liquid biopsies

Fig. 7

DESeq2 identified 47 DE genes between healthy and early-stage NSCLC cohorts, using platelet-derived EVs as biomarker source. (A) Volcano plot showing that no DE genes were found between the two cohorts, based on the triple-coated EV dataset. Cut-offs were defined for adjusted p-values (0.05, Y axis) and log2 fold change (2, X axis). (B) Volcano plot showing DE genes between the two cohorts, based on the platelet-derived EV dataset. Cut-offs were defined for adjusted p-values (0.05, Y axis) and log2 fold change (2, X axis). Upregulated and downregulated genes were depicted by green and red circles, respectively

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