Fig. 2From: Current advances and future perspectives on the functional roles and clinical implications of circular RNAs in esophageal squamous cell carcinoma: more influential than expectedFunction of circRNAs. A EIciRNA and EcRNA can interact with U1 snRNP to regulate host gene transcription in nucleus; In cytoplasm, (B) circRNAs act as miRNA sponge to reduce the function of miRNA; CÂ circRNAs can bind and sequester proteins; DÂ circRNAs can be translated into polypeptideBack to article page