Fig. 3

Temporal profiles of serum biomarkers in footballers with SRC. a Serum concentrations of NfL were increased from baseline (i.e. pre-season) at 6-days (*p=0.012) and 13-days (**p=0.003) after SRC in males. b Tau concentrations in serum were elevated at 13-days compared to baseline in male footballers (*p=0.039). c No changes in UCHL1 levels where found after SRC. d Serum GFAP was elevated at 2-days after SRC in males (***p< 0.001). No differences in serum NfL, tau, UCHL1 and tau were found in females diagnosed with SRC. Individual participant results are plotted, along the group mean ± SEM. Non-concussed controls are included as point of reference, and were not included in this statistical analysis. Note that serum biomarker data was transformed for statistical analysis as described in the methods