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Table 1 Clinicopathological data of Normal Esophagus and Esophageal Tumor patient’s

From: A DNA methylation-based test for esophageal cancer detection

Clinicopathological Features

Esophageal Tumor Samples

Normal Esophagus

Naïve Tumors

Post ChT/RTa Treatment Tumors

Patients (no.)

88

36

56

Age median (range)

63 (37–83)

60 (44–73)

66 (36–84)

Sex (no.)

 Man

74

31

37

 Woman

14

5

19

Histological subtype (no.)

  

n.a.

 Adenocarcinoma

40

16

 

 Squamous Cell Carcinoma

48

20

 

Localization (no.)

  

n.a.

 Upper

3

 

 Middle

27

5

 

 Lower

30

18

 

GEJb

28

13

 

pT Stage/ypT Stage

  

n.a.

 pT1/ypT1

16

5

 

 pT2/ypT2

14

7

 

 pT3/ypT3

56

23

 

 pT4/ypT4

2

1

 

pN Stage/ ypN Stage

  

n.a.

 pN0/ypN0

39

17

 

 pN1/ypN1

17

7

 

 pN2/ypN2

21

6

 

 pN3/ypN3

11

6

 

Stage

  

n.a.

 I

13

4

 

 II

32

6

 

 III

28

19

 

 IV

15

7

 
  1. aChT/RT Chemotherapy and/or Radiotherapy, b GEJ Gastroesophageal Junction, n.a non- applicable