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Table 1 Comparison of clinical variables between SLE patients and healthy controls

From: Assessment of serum macrophage migration inhibitory factor (MIF), adiponectin, and other adipokines as potential markers of proteinuria and renal dysfunction in lupus nephritis: a cross-sectional study

Variable

SLE

n = 196

Healthy Controls

n = 52

p

Age (years) a

45 (18–73)

47 (22–54)

0.87

Gender b

196 (100)

52 (100)

Mexican-Mestizo b

196 (100)

52 (100)

BMI (kg/m2) a

27.3 (17.7–40.0)

27.9 (18.4–47.3)

0.86

SLE duration (years) a

8.3 (2–28)

C3 fraction complement (mg/dL) a

142.0 (42.0–252.0)

C4 fraction complement (mg/dL) a

31 (6.6–71.7)

Positive anti-dsDNA b

55 (28.1)

SLEDAI (score) a

2 (0–12)

rSLEDAI (score) a

0 (0–12)

 - Renal-SLE patients b

43 (21.9)

SLICC/ACR (score) a

1 (0–5)

MEX-SLEDAI (score) a

1 (0–10)

Glucocorticoids b

196 (100)

 - Prednisone > 10 mg/day b

60 (30.6)

Immunosuppressive drugs b

145 (74.0)

 - Azathioprine users b

91 (46.4)

 - Cyclophosphamide users b

13 (6.6)

 - Mycophenolate users b

56 (28.5)

Other drugs (Methotrexate) b

27 (13.8)

  
  1. a Data expressed as medians and ranges (minimum and maximum value). b Data provided in frequencies (percentages). SLE Systemic Lupus Erythematosus, SLEDAI original SLE Disease Activity Index, high score indicates higher disease activity, SLICC/ACR Systemic Lupus International Collaborating Clinics/American College of Rheumatology, rSLEDAI Renal-SLEDAI score (includes proteinuria greater than 0.5 g in 24 h, persistent hematuria, leucocytes on urine or urine casts -granulocytes or erythrocytes-), higher score indicates high renal disease activity. MEX-SLEDAI: Version of SLEDAI validated in Mexico. Comparisons between proportions: Chi- square (or Fisher exact test if required). Comparisons between quantitative variables: Mann-Whitney U test